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Evolutionary drivers of antibiotic resistance in Pseudomonas aeruginosa populations from critically ill patients (ID Epi Seminar Series)

2022/03/31 @ 1:00 pm - 2:00 pm

Craig MacLean photo
Presented by Craig MacLean, Professor of Evolution and Microbiology at the University of Oxford, Department of Zoology. Register for the event here.

Professor Craig MacLean has a longstanding interest in understanding how ecological and genetic processes interact to drive adaptation in microbial populations. His doctoral research at McGill University (2000-2004) investigated the causes of metabolic adaptive radiation in Pseudomonas fluorescens using experimental evolution. His postdoctoral work at Imperial College London (2005-2007) investigated metabolic cooperation and competition in yeasts. Prof. MacLean moved to Oxford as a lecturer in the Department of Zoology in 2007 and was able to establish his own research group when he was awarded a University Research Fellowship from the Royal Society in 2009. Early research in the MacLean lab focused on studying the evolutionary drivers of antibiotic resistance in pathogenic bacteria using a combination of experimental evolution, genomics, and mathematical modelling. More recently, they have shifted the emphasis of their work to studying the drivers of resistance in clinical settings.

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1:00 pm - 2:00 pm