Publications – Center for Communicable Disease Dynamics

Sink-traps are a major source for carbapenemase-producing Enterobacteriaceae transmission.

Author(s): Regev-Yochay G, Margalit I, Smollan G, Rapaport R, Tal I, Hanage WP, Pinas Zade N, Jaber H, Taylor BP, Che Y, Rahav G, Zimlichman E, Keller NJournal: Infect Control Hosp EpidemiolPMID: 38149351 March 2024

We studied the extent of carbapenemase-producing Enterobacteriaceae (CPE) sink contamination and transmission to patients in a nonoutbreak setting.

Enterobacteriaceae isolated from patients share antibiotic resistance conferring plasmids recently acquired from those isolated from sinks in the same treatment room

Author(s): Taylor BP, Che Y, Passarelli H, Smollan G, Cohen C, Rapaport R, Tal I, Zade NP, Jaber H, Keller N, Hanage WP, Regev-Yochay GJournal: bioRxiv November 2022

Identifying how and where pathogens acquire antibiotic resistance is crucial to developing effective strategies to limit its spread. Many bacterial…

SARS-CoV-2 breakthrough infections in vaccinated individuals: measurement, causes and impact.

Author(s): Lipsitch M, Krammer F, Regev-Yochay G, Lustig Y, Balicer RDJournal: Nat Rev ImmunolPMID: 34876702 December 2021

Breakthrough infections with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in fully vaccinated individuals are receiving intense scrutiny because of…

Decreased infectivity following BNT162b2 vaccination: A prospective cohort study in Israel.

Author(s): Regev-Yochay G, Amit S, Bergwerk M, Lipsitch M, Leshem E, Kahn R, Lustig Y, Cohen C, Doolman R, Ziv A, Novikov I, Rubin C, Gimpelevich I, Huppert A, Rahav G, Afek A, Kreiss YJournal: Lancet Reg Health EurPMID: 34250518 August 2021

BNT162b2 was shown to be 92% effective in preventing COVID-19. Prioritizing vaccine rollout, and achievement of herd immunity depend on…

Covid-19 Breakthrough Infections in Vaccinated Health Care Workers.

Author(s): Bergwerk M, Gonen T, Lustig Y, Amit S, Lipsitch M, Cohen C, Mandelboim M, Gal Levin E, Rubin C, Indenbaum V, Tal I, Zavitan M, Zuckerman N, Bar-Chaim A, Kreiss Y, Regev-Yochay GJournal: N Engl J MedPMID: 34320281 July 2021

Despite the high efficacy of the BNT162b2 messenger RNA vaccine against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), rare breakthrough…

Real World Performance of SARS-CoV-2 Antigen Rapid Diagnostic Tests in Various Clinical Settings

Author(s): Regev-Yochay G, Kriger O, Beni S, Rubin C, Mina MJ, Mechnik B, Hason S, Biber E, Nadaf B, Kreiss Y, Amit SJournal: medRxiv March 2021

Several uses of Antigen rapid diagnostic tests (Ag-RDT) have been suggested. Analytical studies reported high specificity yet with lower sensitivity…

Determinants of Staphylococcus aureus carriage in the developing infant nasal microbiome.

Author(s): Accorsi EK, Franzosa EA, Hsu T, Joice Cordy R, Maayan-Metzger A, Jaber H, Reiss-Mandel A, Kline M, DuLong C, Lipsitch M, Regev-Yochay G, Huttenhower CJournal: Genome BiolPMID: 33308267 December 2020

Staphylococcus aureus is a leading cause of healthcare- and community-associated infections and can be difficult to treat due to antimicrobial…

Characteristics of Clinically Asymptomatic Patients with SARS-CoV-2 Infections, Case Series.

Author(s): Goldenfeld M, Nir-Paz R, Segal G, Bar-On E, Mendelson E, Mandelboim M, Wolf DG, Marom EM, Israely T, Achdout H, Rahav G, Hanage WP, Regev-Yochay GJournal: Prehosp Disaster MedPMID: 33198831 November 2020

Up until now, there is much debate about the role of asymptomatic patients and pauci-symptomatic patients in severe acute respiratory…

Genomic epidemiology of meticillin-resistant Staphylococcus aureus ST22 widespread in communities of the Gaza Strip, 2009.

Author(s): Chang Q, Abuelaish I, Biber A, Jaber H, Callendrello A, Andam CP, Regev-Yochay G, Hanage WP, On Behalf Of The Picr Study GroupJournal: Euro SurveillPMID: 30153881 August 2018

BackgroundRemarkably high carriage prevalence of a community-associated meticillin-resistant (MRSA) strain of sequence type (ST) 22 in the Gaza strip was…

Antibiotics in agriculture and the risk to human health: how worried should we be?

Author(s): Chang Q, Wang W, Regev-Yochay G, Lipsitch M, Hanage WPJournal: Evol ApplPMID: 25861382 March 2015

The use of antibiotics in agriculture is routinely described as a major contributor to the clinical problem of resistant disease…