Publications – Center for Communicable Disease Dynamics

Recent advances in the molecular epidemiology of clinical malaria.

Author(s): Recker M, Bull PC, Buckee COJournal: F1000ResPMID: 30135713 July 2018

Human malaria is a complex disease that can show a wide array of clinical outcomes, from asymptomatic carriage and chronic…

Plasmodium falciparum var gene expression homogeneity as a marker of the host-parasite relationship under different levels of naturally acquired immunity to malaria.

Author(s): Warimwe GM, Recker M, Kiragu EW, Buckee CO, Wambua J, Musyoki JN, Marsh K, Bull PCJournal: PLoS OnePMID: 23922996 July 2013

Acquired immunity to Plasmodium falciparum infection causes a change from frequent, sometimes life-threatening, malaria in young children to asymptomatic, chronic…

Evolution of the multi-domain structures of virulence genes in the human malaria parasite, Plasmodium falciparum.

Author(s): Buckee CO, Recker MJournal: PLoS Comput BiolPMID: 22511852 January 2012

The var gene family of Plasmodium falciparum encodes the immunodominant variant surface antigens PfEMP1. These highly polymorphic proteins are important…

Role of stochastic processes in maintaining discrete strain structure in antigenically diverse pathogen populations.

Author(s): Buckee CO, Recker M, Watkins ER, Gupta SJournal: Proc Natl Acad Sci U S APMID: 21876129 September 2011

Many highly diverse pathogen populations appear to exist stably as discrete antigenic types despite evidence of genetic exchange. It has…

Antigenic variation in Plasmodium falciparum malaria involves a highly structured switching pattern.

Author(s): Recker M, Buckee CO, Serazin A, Kyes S, Pinches R, Christodoulou Z, Springer AL, Gupta S, Newbold CIJournal: PLoS PathogPMID: 21408201 March 2011

Many pathogenic bacteria, fungi, and protozoa achieve chronic infection through an immune evasion strategy known as antigenic variation. In the…