Publications

Vaccination Drives Changes in Metabolic and Virulence Profiles of Streptococcus pneumoniae.

Author(s): Watkins ER, Penman BS, Lourenço J, Buckee CO, Maiden MC, Gupta S|Journal: PLoS Pathog|PMID: 26181911| July 2015

The bacterial pathogen, Streptococcus pneumoniae (the pneumococcus), is a leading cause of life-threatening illness and death worldwide. Available conjugate vaccines…

Contrasting within- and between-host immune selection shapes Neisseria Opa repertoires.

Author(s): Watkins ER, Grad YH, Gupta S, Buckee CO|Journal: Sci Rep|PMID: 25296566| October 2014

Pathogen evolution is influenced strongly by the host immune response. Previous studies of the effects of herd immunity on the…

Role of stochastic processes in maintaining discrete strain structure in antigenically diverse pathogen populations.

Author(s): Buckee CO, Recker M, Watkins ER, Gupta S|Journal: Proc Natl Acad Sci U S A|PMID: 21876129| September 2011

Many highly diverse pathogen populations appear to exist stably as discrete antigenic types despite evidence of genetic exchange. It has…