Publications – Center for Communicable Disease Dynamics

Individual quarantine versus active monitoring of contacts for the mitigation of COVID-19: a modelling study.

Author(s): Peak CM, Kahn R, Grad YH, Childs LM, Lipsitch M, Buckee COJournal: Lancet Infect DisPMID: 32445710 May 2020

Voluntary individual quarantine and voluntary active monitoring of contacts are core disease control strategies for emerging infectious diseases such as…

Comparative Impact of Individual Quarantine vs. Active Monitoring of Contacts for the Mitigation of COVID-19: a modelling study.

Author(s): Peak CM, Kahn R, Grad YH, Childs LM, Li R, Lipsitch M, Buckee COJournal: medRxivPMID: 32511440 April 2020

Voluntary individual quarantine and voluntary active monitoring of contacts are core disease control strategies for emerging infectious diseases, such as…

Exposing Anopheles mosquitoes to antimalarials blocks Plasmodium parasite transmission.

Author(s): Paton DG, Childs LM, Itoe MA, Holmdahl IE, Buckee CO, Catteruccia FJournal: NaturePMID: 30814727 February 2019

Bites of Anopheles mosquitoes transmit Plasmodium falciparum parasites that cause malaria, which kills hundreds of thousands of people every year.…

Resistance to Plasmodium falciparum in sickle cell trait erythrocytes is driven by oxygen-dependent growth inhibition.

Author(s): Archer NM, Petersen N, Clark MA, Buckee CO, Childs LM, Duraisingh MTJournal: Proc Natl Acad Sci U S APMID: 29946035 July 2018

Sickle cell trait (AS) confers partial protection against lethal malaria. Multiple mechanisms for this have been proposed, with a recent…

Simulating within-vector generation of the malaria parasite diversity.

Author(s): Childs LM, Prosper OFJournal: PLoS OnePMID: 28542484 May 2017

Plasmodium falciparum, the most virulent human malaria parasite, undergoes asexual reproduction within the human host, but reproduces sexually within its…

Comparing nonpharmaceutical interventions for containing emerging epidemics.

Author(s): Peak CM, Childs LM, Grad YH, Buckee COJournal: Proc Natl Acad Sci U S APMID: 28351976 April 2017

Strategies for containing an emerging infectious disease outbreak must be nonpharmaceutical when drugs or vaccines for the pathogen do not…

Disrupting Mosquito Reproduction and Parasite Development for Malaria Control.

Author(s): Childs LM, Cai FY, Kakani EG, Mitchell SN, Paton D, Gabrieli P, Buckee CO, Catteruccia FJournal: PLoS PathogPMID: 27977810 December 2016

The control of mosquito populations with insecticide treated bed nets and indoor residual sprays remains the cornerstone of malaria reduction…

The role of interconnectivity in control of an Ebola epidemic.

Author(s): Blackwood JC, Childs LMJournal: Sci RepPMID: 27383118 July 2016

Several West African countries - Liberia, Sierra Leone and Guinea - experienced significant morbidity and mortality during the largest Ebola…

Wolbachia infections in natural Anopheles populations affect egg laying and negatively correlate with Plasmodium development.

Author(s): Shaw WR, Marcenac P, Childs LM, Buckee CO, Baldini F, Sawadogo SP, Dabiré RK, Diabaté A, Catteruccia FJournal: Nat CommunPMID: 27243367 May 2016

The maternally inherited alpha-proteobacterium Wolbachia has been proposed as a tool to block transmission of devastating mosquito-borne infectious diseases like…

Variation in infection length and superinfection enhance selection efficiency in the human malaria parasite.

Author(s): Chang HH, Childs LM, Buckee COJournal: Sci RepPMID: 27193195 May 2016

The capacity for adaptation is central to the evolutionary success of the human malaria parasite Plasmodium falciparum. Malaria epidemiology is…