Publications

Multiple blood feeding in mosquitoes shortens the Plasmodium falciparum incubation period and increases malaria transmission potential.

Author(s): Shaw WR, Holmdahl IE, Itoe MA, Werling K, Marquette M, Paton DG, Singh N, Buckee CO, Childs LM, Catteruccia F|Journal: PLoS Pathog|PMID: 33382824| December 2020

Many mosquito species, including the major malaria vector Anopheles gambiae, naturally undergo multiple reproductive cycles of blood feeding, egg development…

Individual quarantine versus active monitoring of contacts for the mitigation of COVID-19: a modelling study.

Author(s): Peak CM, Kahn R, Grad YH, Childs LM, Lipsitch M, Buckee CO|Journal: Lancet Infect Dis|PMID: 32445710| May 2020

Voluntary individual quarantine and voluntary active monitoring of contacts are core disease control strategies for emerging infectious diseases such as…

Comparative Impact of Individual Quarantine vs. Active Monitoring of Contacts for the Mitigation of COVID-19: a modelling study.

Author(s): Peak CM, Kahn R, Grad YH, Childs LM, Li R, Lipsitch M, Buckee CO|Journal: medRxiv|PMID: 32511440| April 2020

Voluntary individual quarantine and voluntary active monitoring of contacts are core disease control strategies for emerging infectious diseases, such as…

Exposing Anopheles mosquitoes to antimalarials blocks Plasmodium parasite transmission.

Author(s): Paton DG, Childs LM, Itoe MA, Holmdahl IE, Buckee CO, Catteruccia F|Journal: Nature|PMID: 30814727| February 2019

Bites of Anopheles mosquitoes transmit Plasmodium falciparum parasites that cause malaria, which kills hundreds of thousands of people every year.…

Resistance to Plasmodium falciparum in sickle cell trait erythrocytes is driven by oxygen-dependent growth inhibition.

Author(s): Archer NM, Petersen N, Clark MA, Buckee CO, Childs LM, Duraisingh MT|Journal: Proc Natl Acad Sci U S A|PMID: 29946035| July 2018

Sickle cell trait (AS) confers partial protection against lethal malaria. Multiple mechanisms for this have been proposed, with a recent…

Comparing nonpharmaceutical interventions for containing emerging epidemics.

Author(s): Peak CM, Childs LM, Grad YH, Buckee CO|Journal: Proc Natl Acad Sci U S A|PMID: 28351976| April 2017

Strategies for containing an emerging infectious disease outbreak must be nonpharmaceutical when drugs or vaccines for the pathogen do not…

Disrupting Mosquito Reproduction and Parasite Development for Malaria Control.

Author(s): Childs LM, Cai FY, Kakani EG, Mitchell SN, Paton D, Gabrieli P, Buckee CO, Catteruccia F|Journal: PLoS Pathog|PMID: 27977810| December 2016

The control of mosquito populations with insecticide treated bed nets and indoor residual sprays remains the cornerstone of malaria reduction…

Wolbachia infections in natural Anopheles populations affect egg laying and negatively correlate with Plasmodium development.

Author(s): Shaw WR, Marcenac P, Childs LM, Buckee CO, Baldini F, Sawadogo SP, Dabiré RK, Diabaté A, Catteruccia F|Journal: Nat Commun|PMID: 27243367| May 2016

The maternally inherited alpha-proteobacterium Wolbachia has been proposed as a tool to block transmission of devastating mosquito-borne infectious diseases like…

Variation in infection length and superinfection enhance selection efficiency in the human malaria parasite.

Author(s): Chang HH, Childs LM, Buckee CO|Journal: Sci Rep|PMID: 27193195| May 2016

The capacity for adaptation is central to the evolutionary success of the human malaria parasite Plasmodium falciparum. Malaria epidemiology is…

Altered drug susceptibility during host adaptation of a Plasmodium falciparum strain in a non-human primate model.

Author(s): Obaldía N 3rd, Dow GS, Gerena L, Kyle D, Otero W, Mantel PY, Baro N, Daniels R, Mukherjee A, Childs LM, Buckee C, Duraisingh MT, Volkman SK, Wirth DF, Marti M|Journal: Sci Rep|PMID: 26880111| February 2016

Infections with Plasmodium falciparum, the most pathogenic of the Plasmodium species affecting man, have been reduced in part due to…