Deep–sequence phylogenetics to quantify patterns of HIV transmission in the context of a universal testing and treatment trial — BCPP/ Ya Tsie trial

Author(s): Magosi LE, Zhang Y, Golubchick T, Gruttola VD, Tchetgen EJT, Novitsky V, Moore J, Bachanas P, Segolodi T, Lebelonyane R, Holme MP, Moyo S, Makhema J, Lockman S, Fraser C, Essex M, Lipsitch MJournal: medRxiv June 2021
Mathematical models predict that community–wide access to HIV testing–and–treatment can rapidly and substantially reduce new HIV infections. Yet several large…

Frequency-dependent selection can forecast evolution in Streptococcus pneumoniae.

Author(s): Azarian T, Martinez PP, Arnold BJ, Qiu X, Grant LR, Corander J, Fraser C, Croucher NJ, Hammitt LL, Reid R, Santosham M, Weatherholtz RC, Bentley SD, O'Brien KL, Lipsitch M, Hanage WPJournal: PLoS BiolPMID: 33091022 October 2020
Predicting how pathogen populations will change over time is challenging. Such has been the case with Streptococcus pneumoniae, an important…