Macrolide and Nonmacrolide Resistance with Mass Azithromycin Distribution.

Author(s): Doan T, Worden L, Hinterwirth A, Arzika AM, Maliki R, Abdou A, Zhong L, Chen C, Cook C, Lebas E, O'Brien KS, Oldenburg CE, Chow ED, Porco TC, Lipsitch M, Keenan JD, Lietman TMJournal: N Engl J MedPMID: 33176084 November 2020
Mass distribution of azithromycin to preschool children twice yearly for 2 years has been shown to reduce childhood mortality in…

The role of “spillover” in antibiotic resistance.

Author(s): Olesen SW, Lipsitch M, Grad YHJournal: Proc Natl Acad Sci U S APMID: 33139558 November 2020
Antibiotic use is a key driver of antibiotic resistance. Understanding the quantitative association between antibiotic use and resulting resistance is…

Frequency-dependent selection can forecast evolution in Streptococcus pneumoniae.

Author(s): Azarian T, Martinez PP, Arnold BJ, Qiu X, Grant LR, Corander J, Fraser C, Croucher NJ, Hammitt LL, Reid R, Santosham M, Weatherholtz RC, Bentley SD, O'Brien KL, Lipsitch M, Hanage WPJournal: PLoS BiolPMID: 33091022 October 2020
Predicting how pathogen populations will change over time is challenging. Such has been the case with Streptococcus pneumoniae, an important…

Scientific consensus on the COVID-19 pandemic: we need to act now.

Author(s): Alwan NA, Burgess RA, Ashworth S, Beale R, Bhadelia N, Bogaert D, Dowd J, Eckerle I, Goldman LR, Greenhalgh T, Gurdasani D, Hamdy A, Hanage WP, Hodcroft EB, Hyde Z, Kellam P, Kelly-Irving M, Krammer F, Lipsitch M, McNally A, McKee M, Nouri A, Pimenta D, Priesemann V, Rutter H, Silver J, Sridhar D, Swanton C, Walensky RP, Yamey G, Ziauddeen HJournal: LancetPMID: 33069277 October 2020
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has infected more than 35 million people globally, with more than 1 million…