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Publications

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Evaluating spatially adaptive guidelines for the treatment of gonorrhea to reduce the incidence of gonococcal infection and increase the effective lifespan of antibiotics.

Author(s): Yaesoubi R, Cohen T, Hsu K, Gift TL, St Cyr SB, Salomon JA, Grad YH|Journal: PLoS Comput Biol|PMID: 35139073| February 2022
In the absence of point-of-care gonorrhea diagnostics that report antibiotic susceptibility, gonorrhea treatment is empiric and determined by standardized guidelines.…

Evaluating the reliability of mobility metrics from aggregated mobile phone data as proxies for SARS-CoV-2 transmission in the USA: a population-based study.

Author(s): Kishore N, Taylor AR, Jacob PE, Vembar N, Cohen T, Buckee CO, Menzies NA|Journal: Lancet Digit Health|PMID: 34740555| November 2021
In early 2020, the response to the SARS-CoV-2 pandemic focused on non-pharmaceutical interventions, some of which aimed to reduce transmission…

Reporting practices for genomic epidemiology of tuberculosis: a systematic review of the literature using STROME-ID guidelines as a benchmark.

Author(s): Cheng B, Behr MA, Howden BP, Cohen T, Lee RS|Journal: Lancet Microbe|PMID: 33842904| August 2021
Pathogen genomics have become increasingly important in infectious disease epidemiology and public health. The Strengthening the Reporting of Molecular Epidemiology…

The relationship between human mobility measures and SAR-Cov-2 transmission varies by epidemic phase and urbanicity: results from the United States

Author(s): Kishore N, Taylor AR, Jacob PE, Vembar N, Cohen T, Menzies NA, Buckee C|Journal: medRxiv| April 2021
Global efforts to prevent the spread of the SARS-COV-2 pandemic in early 2020 focused on non-pharmaceutical interventions like social distancing;…

Children as sentinels of tuberculosis transmission: disease mapping of programmatic data.

Author(s): Gunasekera KS, Zelner J, Becerra MC, Contreras C, Franke MF, Lecca L, Murray MB, Warren JL, Cohen T|Journal: BMC Med|PMID: 32873309| September 2020
Identifying hotspots of tuberculosis transmission can inform spatially targeted active case-finding interventions. While national tuberculosis programs maintain notification registers which…

Adaptive guidelines for the treatment of gonorrhea to increase the effective life span of antibiotics among men who have sex with men in the United States: A mathematical modeling study.

Author(s): Yaesoubi R, Cohen T, Hsu K, Gift TL, Chesson H, Salomon JA, Grad YH|Journal: PLoS Med|PMID: 32243443| April 2020
The rise of gonococcal antimicrobial resistance highlights the need for strategies that extend the clinically useful life span of antibiotics.…

Polyclonal Pulmonary Tuberculosis Infections and Risk for Multidrug Resistance, Lima, Peru.

Author(s): Nathavitharana RR, Shi CX, Chindelevitch L, Calderon R, Zhang Z, Galea JT, Contreras C, Yataco R, Lecca L, Becerra MC, Murray MB, Cohen T|Journal: Emerg Infect Dis|PMID: 29048297| November 2017
Because within-host Mycobacterium tuberculosis diversity complicates diagnosis and treatment of tuberculosis (TB), we measured diversity prevalence and associated factors among…

Identifying Hotspots of Multidrug-Resistant Tuberculosis Transmission Using Spatial and Molecular Genetic Data.

Author(s): Zelner JL, Murray MB, Becerra MC, Galea J, Lecca L, Calderon R, Yataco R, Contreras C, Zhang Z, Manjourides J, Grenfell BT, Cohen T|Journal: J Infect Dis|PMID: 26175455| January 2016
We aimed to identify and determine the etiology of "hotspots" of concentrated multidrug-resistant tuberculosis (MDR-tuberculosis) risk in Lima, Peru.

The potential impact of coinfection on antimicrobial chemotherapy and drug resistance.

Author(s): Birger RB, Kouyos RD, Cohen T, Griffiths EC, Huijben S, Mina MJ, Volkova V, Grenfell B, Metcalf CJE|Journal: Trends Microbiol|PMID: 26028590| September 2015
Across a range of pathogens, resistance to chemotherapy is a growing problem in both public health and animal health. Despite…

How could preventive therapy affect the prevalence of drug resistance? Causes and consequences.

Author(s): Kunkel A, Colijn C, Lipsitch M, Cohen T|Journal: Philos Trans R Soc Lond B Biol Sci|PMID: 25918446| June 2015
Various forms of preventive and prophylactic antimicrobial therapies have been proposed to combat HIV (e.g. pre-exposure prophylaxis), tuberculosis (e.g. isoniazid…

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