Publications – Center for Communicable Disease Dynamics

Dual TCR-alpha expression on MAIT cells as a potential confounder of TCR interpretation

Author(s): Suliman S, Kjer-Nielsen L, Iwany S, Lopez K, Loh L, Kedzierska K, Ocampo TA, Corbett A, McCluskey J, Rossjohn J, Leon S, Calderon R, Lecca L, Murray MB, Moody B, Rhijn IVJournal: bioRxiv March 2021

Mucosal-associated invariant T (MAIT) cells are innate-like T cells that are highly abundant in human blood and tissues. Most MAIT…

Synthetic mycobacterial diacyl trehaloses reveal differential recognition by human T cell receptors and the C-type lectin Mincle.

Author(s): Reijneveld JF, Holzheimer M, Young DC, Lopez K, Suliman S, Jimenez J, Calderon R, Lecca L, Murray MB, Ishikawa E, Yamasaki S, Minnaard AJ, Moody DB, Van Rhijn IJournal: Sci RepPMID: 33479373 January 2021

The cell wall of Mycobacterium tuberculosis is composed of diverse glycolipids which potentially interact with the human immune system. To…

CD1b Tetramers Broadly Detect T Cells That Correlate With Mycobacterial Exposure but Not Tuberculosis Disease State.

Author(s): Lopez K, Iwany SK, Suliman S, Reijneveld JF, Ocampo TA, Jimenez J, Calderon R, Lecca L, Murray MB, Moody DB, Van Rhijn IJournal: Front ImmunolPMID: 32117314 February 2020

The non-polymorphic nature of CD1 proteins creates a situation in which T cells with invariant T cell receptors (TCRs), like…