Publications

Identification of bile acid and fatty acid species as candidate rapidly bactericidal agents for topical treatment of gonorrhoea.

Author(s): Palace SG, Fryling KE, Li Y, Wentworth AJ, Traverso G, Grad YH|Journal: J Antimicrob Chemother|PMID: 34245280| July 2021

Novel therapeutic strategies are urgently needed for Neisseria gonorrhoeae, given its increasing antimicrobial resistance. Treatment of oropharyngeal N. gonorrhoeae infections…

RNA polymerase mutations cause cephalosporin resistance in clinical Neisseria gonorrhoeae isolates.

Author(s): Palace SG, Wang Y, Rubin DH, Welsh MA, Mortimer TD, Cole K, Eyre DW, Walker S, Grad YH|Journal: Elife|PMID: 32011233| February 2020

Increasing resistance to ceftriaxone, the last antibiotic recommended for empiric gonorrhea treatment, poses an urgent public health threat. However, the…