Publications – Center for Communicable Disease Dynamics

The inter-continental population dynamics of Neisseria gonorrhoeae

Author(s): Osnes MN, Brynildsrud OB, Alfsnes K, McKeand SA, Ross J, Town K, de Korne-Elenbaas J, van Dam A, Bruisten S, de Blasio BF, Caugant DA, Grad YH, Williamson DA, Balloux F, Didelot X, Eldholm V, Van Dorp LJournal: bioRxiv August 2023

Neisseria gonorrhoeae is a globally distributed sexually transmitted bacterial pathogen. Recent studies have revealed that its evolution has been shaped…

Adaptation to the cervical environment is associated with increased antibiotic susceptibility in Neisseria gonorrhoeae.

Author(s): Ma KC, Mortimer TD, Hicks AL, Wheeler NE, Sánchez-Busó L, Golparian D, Taiaroa G, Rubin DHF, Wang Y, Williamson DA, Unemo M, Harris SR, Grad YHJournal: Nat CommunPMID: 32807804 August 2020

Neisseria gonorrhoeae is an urgent public health threat due to rapidly increasing incidence and antibiotic resistance. In contrast with the…

Targeted surveillance strategies for efficient detection of novel antibiotic resistance variants.

Author(s): Hicks AL, Kissler SM, Mortimer TD, Ma KC, Taiaroa G, Ashcroft M, Williamson DA, Lipsitch M, Grad YHJournal: ElifePMID: 32602459 June 2020

Genotype-based diagnostics for antibiotic resistance represent a promising alternative to empiric therapy, reducing inappropriate antibiotic use. However, because such assays…