Publications – Center for Communicable Disease Dynamics

Densely sampled viral trajectories suggest longer duration of acute infection with B.1.1.7 variant relative to non-B.1.1.7 SARS-CoV-2

Author(s): Kissler SM, Fauver JR, Mack C, Tai C, Breban M, Watkins AE, Samant R, Anderson D, Ho D, Grubaugh ND, Grad YJournal: medRxiv February 2021

To test whether acute infection with B.1.1.7 is associated with higher or more sustained nasopharyngeal viral concentrations, we assessed longitudinal…

SARS-CoV-2 viral dynamics in acute infections

Author(s): Kissler SM, Fauver JR, Mack C, Olesen SW, Tai C, Shiue KY, Kalinich C, Jednak S, Ott I, Vogels C, Wohlgemuth J, Weisberger J, DiFiori J, Anderson DJ, Mancell J, Ho D, Grubaugh ND, Grad YHJournal: medRxiv December 2020

SARS-CoV-2 infections are characterized by viral proliferation and clearance phases and can be followed by low-level viral RNA shedding. The…

Making Sense of Mutation: What D614G Means for the COVID-19 Pandemic Remains Unclear.

Author(s): Grubaugh ND, Hanage WP, Rasmussen ALJournal: CellPMID: 32697970 July 2020

In this issue of Cell, Korber et al. found that a SARS-CoV-2 variant in the spike protein D614G rapidly became dominant…