Burden of antimicrobial resistance: compared to what?

Author(s): Marlieke de Kraker, Marc LipsitchJournal: DASH October 2020
There has been an increased focus on the public health burden of antimicrobial resistance (AMR). This raises conceptual challenges such…

The role of “spillover” in antibiotic resistance

Author(s): Scott W. Olesen, Marc Lipsitch, Yonatan H. GradJournal: bioRxiv June 2020
Antibiotic use is a key driver of antibiotic resistance. Understanding the quantitative association between antibiotic use and resulting resistance is…

Social distancing strategies for curbing the COVID-19 epidemic

Author(s): Stephen Kissler, Christine Tedijanto, Marc Lipsitch, Yonatan GradJournal: medRxiv March 2020
The SARS-CoV-2 pandemic is straining healthcare resources worldwide, prompting social distancing measures to reduce transmission intensity. The amount of social…

Predicting evolution using frequency-dependent selection in bacterial populations

Author(s): Taj Azarian, Pamela P Martinez, Brian J Arnold, Lindsay R Grant, Jukka Corander, Christophe Fraser, Nicholas J. Croucher, Laura L Hammitt, Raymond Reid, Mathuram Santosham, Robert C Weatherholtz, Stephen D Bentley, Katherine L O’Brien, Marc Lipsitch, William P HanageJournal: bioRxiv February 2020
Predicting how pathogen populations will change over time is challenging. Such has been the case with Streptococcus pneumoniae, an important…