Publications

Personalizing the empiric treatment of gonorrhea using machine learning models.

Author(s): Murray-Watson RE, Grad YH, St Cyr SB, Yaesoubi R|Journal: PLOS Digit Health|PMID: 39141668| August 2024

Despite the emergence of antimicrobial-resistant (AMR) strains of Neisseria gonorrhoeae, the treatment of gonorrhea remains empiric and according to standardized…

Assessing thresholds of resistance prevalence at which empiric treatment of gonorrhea should change among men who have sex with men in the US: A cost-effectiveness analysis.

Author(s): Yin X, Li Y, Rönn MM, Li S, Yuan Y, Gift TL, Hsu K, Salomon JA, Grad YH, Yaesoubi R|Journal: PLoS Med|PMID: 38976754| July 2024

Since common diagnostic tests for gonorrhea do not provide information about susceptibility to antibiotics, treatment of gonorrhea remains empiric. Antibiotics…

The Impact of Rapid Drug Susceptibility Tests on Gonorrhea Burden and Lifespan of Antibiotic Treatments: A Modeling Study Among Men Who Have Sex With Men in the United States.

Author(s): Yaesoubi R, Xi Q, Hsu K, Gift TL, St Cyr SB, Rönn MM, Salomon JA, Grad YH|Journal: Am J Epidemiol|PMID: 37625444| January 2024

Rapid point-of-care tests that diagnose gonococcal infections and identify susceptibility to antibiotics enable individualized treatment. This could improve patient outcomes…

Resistance-minimising strategies for introducing a novel antibiotic for gonorrhoea treatment: a mathematical modelling study.

Author(s): Reichert E, Yaesoubi R, Rönn MM, Gift TL, Salomon JA, Grad YH|Journal: Lancet Microbe|PMID: 37619582| October 2023

Gonorrhoea is a highly prevalent sexually transmitted infection and an urgent public health concern because of increasing antibiotic resistance in…

Resistance-minimising strategies for introducing a novel antibiotic for gonorrhoea treatment: a mathematical modelling study

Author(s): Reichert E, Yaesoubi R, Rönn MM, Gift TL, Salomon JA, Grad YH|Journal: Lancet Microbe|PMID: 37619582| August 2023

Gonorrhoea is a highly prevalent sexually transmitted infection and an urgent public health concern because of increasing antibiotic resistance in…

Resistance-minimizing strategies for introducing a novel antibiotic for gonorrhea treatment: a mathematical modeling study.

Author(s): Reichert E, Yaesoubi R, Rönn MM, Gift TL, Salomon JA, Grad YH|Journal: medRxiv|PMID: 36824857| February 2023

Gonorrhea is a highly prevalent sexually transmitted infection and an urgent public health concern due to increasing antibiotic resistance. Only…

Generating simple classification rules to predict local surges in COVID-19 hospitalizations.

Author(s): Yaesoubi R, You S, Xi Q, Menzies NA, Tuite A, Grad YH, Salomon JA|Journal: Health Care Manag Sci|PMID: 36692583| January 2023

Low rates of vaccination, emergence of novel variants of SARS-CoV-2, and increasing transmission relating to seasonal changes and relaxation of…

Evaluating spatially adaptive guidelines for the treatment of gonorrhea to reduce the incidence of gonococcal infection and increase the effective lifespan of antibiotics.

Author(s): Yaesoubi R, Cohen T, Hsu K, Gift TL, St Cyr SB, Salomon JA, Grad YH|Journal: PLoS Comput Biol|PMID: 35139073| February 2022

In the absence of point-of-care gonorrhea diagnostics that report antibiotic susceptibility, gonorrhea treatment is empiric and determined by standardized guidelines.…

Simple decision rules to predict local surges in COVID-19 hospitalizations during the winter and spring of 2022.

Author(s): Yaesoubi R, You S, Xi Q, Menzies NA, Tuite A, Grad YH, Salomon JA|Journal: medRxiv|PMID: 34931196| December 2021

Low rates of vaccination, emergence of novel variants of SARS-CoV-2, and increasing transmission relating to seasonal changes leave many U.S.…

Adaptive guidelines for the treatment of gonorrhea to increase the effective life span of antibiotics among men who have sex with men in the United States: A mathematical modeling study.

Author(s): Yaesoubi R, Cohen T, Hsu K, Gift TL, Chesson H, Salomon JA, Grad YH|Journal: PLoS Med|PMID: 32243443| April 2020

The rise of gonococcal antimicrobial resistance highlights the need for strategies that extend the clinically useful life span of antibiotics.…