Widespread sharing of pneumococcal strains in a rural African setting: proximate villages are more likely to share similar strains that are carried at multiple timepoints.

Author(s): Senghore M, Chaguza C, Bojang E, Tientcheu PE, Bancroft RE, Lo SW, Gladstone RA, McGee L, Worwui A, Foster-Nyarko E, Ceesay F, Okoi CB, Klugman KP, Breiman RF, Bentley SD, Adegbola R, Antonio M, Hanage WP, Kwambana-Adams BAJournal: Microb GenomPMID: 35119356 February 2022
The transmission dynamics of in sub-Saharan Africa are poorly understood due to a lack of adequate epidemiological and genomic data.…

The role of interspecies recombinations in the evolution of antibiotic resistant pneumococci.

Author(s): D’Aeth JC, van der Linden MPG, McGee L, de Lencastre H, Turner P, Song JH, Lo SW, Gladstone RA, Sá-Leão R, Ko KS, Hanage WP, Breiman RF, Beall B, Bentley SD, Croucher NJ, GPS Consortium.Journal: ElifePMID: 34259624 July 2021
Multidrug-resistant emerge through the modification of core genome loci through short inter-species homologous recombinations and acquisition of gene cassettes. Both…