Publications – Center for Communicable Disease Dynamics

Multimodally profiling memory T cells from a tuberculosis cohort identifies cell state associations with demographics, environment and disease.

Author(s): Nathan A, Beynor JI, Baglaenko Y, Suliman S, Ishigaki K, Asgari S, Huang CC, Luo Y, Zhang Z, Lopez K, Lindestam Arlehamn CS, Ernst JD, Jimenez J, Calderón RI, Lecca L, Van Rhijn I, Moody DB, Murray MB, Raychaudhuri SJournal: Nat ImmunolPMID: 34031617 May 2021

Multimodal T cell profiling can enable more precise characterization of elusive cell states underlying disease. Here, we integrated single-cell RNA…

Axes of inter-sample variability among transcriptional neighborhoods reveal disease associated cell states in single-cell data

Author(s): Reshef YA, Rumker L, Kang JB, Nathan A, Murray MB, Moody DB, Raychaudhuri SJournal: bioRxiv April 2021

As single-cell datasets grow in sample size, there is a critical need to characterize cell states that vary across samples…