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Limited available evidence supports theoretical predictions of reduced vaccine efficacy at higher exposure dose.

Author(s): Langwig KE, Gomes MGM, Clark MD, Kwitny M, Yamada S, Wargo AR, Lipsitch M|Journal: Sci Rep|PMID: 30824732| May 2019
Understanding the causes of vaccine failure is important for predicting disease dynamics in vaccinated populations and planning disease interventions. Pathogen…

Vaccine Effects on Heterogeneity in Susceptibility and Implications for Population Health Management.

Author(s): Langwig KE, Wargo AR, Jones DR, Viss JR, Rutan BJ, Egan NA, Sá-Guimarães P, Kim MS, Kurath G, Gomes MGM, Lipsitch M|Journal: MBio|PMID: 29162706| November 2017
Heterogeneity in host susceptibility is a key determinant of infectious disease dynamics but is rarely accounted for in assessment of…
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