Publications

History of tuberculosis disease is associated with genetic regulatory variation in Peruvians

Author(s): Suliman S, Nieto-Caballero VE, Asgari S, Lopez K, Iwany SK, Luo Y, Nathan A, Fernandez-Salinas D, Chiñas M, Huang CC, Zhang Z, Leon SR, Calderón RI, Lecca L, Murray M, Rhijn IV, Raychaudhuri S, Moody DB, Gutierrez-Arcelus M|Journal: medRxiv| July 2023

A quarter of humanity is estimated to be latently infected with Mycobacterium tuberculosis (Mtb) with a 5-10% risk of developing…

Spatial scale of tuberculosis transmission in Lima, Peru.

Author(s): Huang CC, Trevisi L, Becerra MC, Calderón RI, Contreras CC, Jimenez J, Lecca LW, Yataco RM, Zhang Z, Murray MB|Journal: Proc Natl Acad Sci U S A|PMID: 36322726| November 2022

Spatially targeted interventions may be effective alternatives to individual or population-based prevention strategies against tuberculosis (TB). However, their efficacy may…

Smoking cessation in tuberculosis patients and the risk of tuberculosis infection in child household contacts.

Author(s): Chu AL, Lecca LW, Calderón RI, Contreras CC, Yataco RM, Zhang Z, Becerra MC, Murray MB, Huang CC|Journal: Clin Infect Dis|PMID: 34049397| May 2021

While previous studies have shown that cigarette smoking increases the infectiousness of tuberculosis patients, the impact of smoking cessation on…

Multimodally profiling memory T cells from a tuberculosis cohort identifies cell state associations with demographics, environment and disease.

Author(s): Nathan A, Beynor JI, Baglaenko Y, Suliman S, Ishigaki K, Asgari S, Huang CC, Luo Y, Zhang Z, Lopez K, Lindestam Arlehamn CS, Ernst JD, Jimenez J, Calderón RI, Lecca L, Van Rhijn I, Moody DB, Murray MB, Raychaudhuri S|Journal: Nat Immunol|PMID: 34031617| May 2021

Multimodal T cell profiling can enable more precise characterization of elusive cell states underlying disease. Here, we integrated single-cell RNA…