Publications

Latent tuberculosis and depressive symptoms in household contacts of persons with active TB: A cohort study

Author(s): Galea JT, Chu AL, Sweetland A, Jimenez J, Yataco R, Calderon R, Zhang Z, Huang CC, Lecca L, Murray MBJournal: medRxiv November 2022

Depression is common among persons with TB and associated with poor clinical outcomes. However, little is known about the relationship…

Spatial scale of tuberculosis transmission in Lima, Peru.

Author(s): Huang CC, Trevisi L, Becerra MC, Calderón RI, Contreras CC, Jimenez J, Lecca LW, Yataco RM, Zhang Z, Murray MBJournal: Proc Natl Acad Sci U S APMID: 36322726 November 2022

Spatially targeted interventions may be effective alternatives to individual or population-based prevention strategies against tuberculosis (TB). However, their efficacy may…

Higher native Peruvian genetic ancestry proportion is associated with tuberculosis progression risk.

Author(s): Asgari S, Luo Y, Huang CC, Zhang Z, Calderon R, Jimenez J, Yataco R, Contreras C, Galea JT, Lecca L, Jones D, Moody DB, Murray MB, Raychaudhuri SJournal: Cell GenomPMID: 35873671 July 2022

We investigated whether ancestry-specific genetic factors affect tuberculosis (TB) progression risk in a cohort of admixed Peruvians. We genotyped 2,105…

The Contribution of Chest Radiography to the Clinical Management of Children Exposed to Tuberculosis

Author(s): Huang CC, Tan Q, Becerra MC, Calderon R, Chiang SS, Contreras C, Lecca L, Jimenez J, Pérez-Vélez CM, Roya-Pabon CL, Yataco R, Xu H, Zhang Z, Murray MJournal: Am J Respir Crit Care MedPMID: 35608549 June 2022

Although World Health Organization guidelines emphasize contact investigation for tuberculosis-exposed children, data that support chest radiography as a useful tool…

Smoking cessation in tuberculosis patients and the risk of tuberculosis infection in child household contacts.

Author(s): Chu AL, Lecca LW, Calderón RI, Contreras CC, Yataco RM, Zhang Z, Becerra MC, Murray MB, Huang CCJournal: Clin Infect DisPMID: 34049397 May 2021

While previous studies have shown that cigarette smoking increases the infectiousness of tuberculosis patients, the impact of smoking cessation on…

Multimodally profiling memory T cells from a tuberculosis cohort identifies cell state associations with demographics, environment and disease.

Author(s): Nathan A, Beynor JI, Baglaenko Y, Suliman S, Ishigaki K, Asgari S, Huang CC, Luo Y, Zhang Z, Lopez K, Lindestam Arlehamn CS, Ernst JD, Jimenez J, Calderón RI, Lecca L, Van Rhijn I, Moody DB, Murray MB, Raychaudhuri SJournal: Nat ImmunolPMID: 34031617 May 2021

Multimodal T cell profiling can enable more precise characterization of elusive cell states underlying disease. Here, we integrated single-cell RNA…

Patients with Cancer Appear More Vulnerable to SARS-CoV-2: A Multicenter Study during the COVID-19 Outbreak.

Author(s): Dai M, Liu D, Liu M, Zhou F, Li G, Chen Z, Zhang Z, You H, Wu M, Zheng Q, Xiong Y, Xiong H, Wang C, Chen C, Xiong F, Zhang Y, Peng Y, Ge S, Zhen B, Yu T, Wang L, Wang H, Liu Y, Chen Y, Mei J, Gao X, Li Z, Gan L, He C, Shi Y, Qi Y, Yang J, Tenen DG, Chai L, Mucci LA, Santillana M, Cai HJournal: Cancer DiscovPMID: 32345594 April 2020

The novel COVID-19 outbreak has affected more than 200 countries and territories as of March 2020. Given that patients with…