Publications – Center for Communicable Disease Dynamics

The Contribution of Chest Radiography to the Clinical Management of Children Exposed to Tuberculosis

Author(s): Huang CC, Tan Q, Becerra MC, Calderon R, Chiang SS, Contreras C, Lecca L, Jimenez J, Pérez-Vélez CM, Roya-Pabon CL, Yataco R, Xu H, Zhang Z, Murray MJournal: Am J Respir Crit Care MedPMID: 35608549 June 2022

Although World Health Organization guidelines emphasize contact investigation for tuberculosis-exposed children, data that support chest radiography as a useful tool…

Treatment Outcomes Among Pregnant Patients With Multidrug-Resistant Tuberculosis: A Systematic Review and Meta-analysis.

Author(s): Alene KA, Murray MB, van de Water BJ, Becerra MC, Atalell KA, Nicol MP, Clements ACAJournal: JAMA Netw OpenPMID: 35687333 June 2022

The management of multidrug-resistant tuberculosis (MDR-TB) during pregnancy is challenging, yet no systematic synthesis of evidence has accurately measured treatment…

Prediction Tool to Identify Children at Highest Risk of Tuberculosis Disease Progression Among Those Exposed at Home.

Author(s): Brooks MB, Lecca L, Contreras C, Calderon R, Yataco R, Galea J, Huang CC, Murray MB, Becerra MCJournal: Open Forum Infect DisPMID: 34805431 November 2021

There is a dearth of research to understand which children, among those who are exposed at home to tuberculosis (TB),…

Smoking cessation in tuberculosis patients and the risk of tuberculosis infection in child household contacts.

Author(s): Chu AL, Lecca LW, Calderón RI, Contreras CC, Yataco RM, Zhang Z, Becerra MC, Murray MB, Huang CCJournal: Clin Infect DisPMID: 34049397 May 2021

While previous studies have shown that cigarette smoking increases the infectiousness of tuberculosis patients, the impact of smoking cessation on…

Children as sentinels of tuberculosis transmission: disease mapping of programmatic data.

Author(s): Gunasekera KS, Zelner J, Becerra MC, Contreras C, Franke MF, Lecca L, Murray MB, Warren JL, Cohen TJournal: BMC MedPMID: 32873309 September 2020

Identifying hotspots of tuberculosis transmission can inform spatially targeted active case-finding interventions. While national tuberculosis programs maintain notification registers which…

Mycobacterium tuberculosis Beijing Lineage and Risk for Tuberculosis in Child Household Contacts, Peru.

Author(s): Huang CC, Chu AL, Becerra MC, Galea JT, Calderon R, Contreras C, Yataco R, Zhang Z, Lecca L, Murray MBJournal: Emerg Infect DisPMID: 32091363 March 2020

Few studies have prospectively compared the relative transmissibility and propensity to cause disease of Mycobacterium tuberculosis Beijing strains with other…

Two clinical prediction tools to improve tuberculosis contact investigation.

Author(s): Li R, Nordio F, Huang CC, Contreras C, Calderon R, Yataco R, Galea JT, Zhang Z, Becerra MC, Lecca L, Murray MBJournal: Clin Infect DisPMID: 31905406 January 2020

Efficient contact investigation strategies are needed for the early diagnosis of TB disease and treatment of latent TB infections.

Polyclonal Pulmonary Tuberculosis Infections and Risk for Multidrug Resistance, Lima, Peru.

Author(s): Nathavitharana RR, Shi CX, Chindelevitch L, Calderon R, Zhang Z, Galea JT, Contreras C, Yataco R, Lecca L, Becerra MC, Murray MB, Cohen TJournal: Emerg Infect DisPMID: 29048297 November 2017

Because within-host Mycobacterium tuberculosis diversity complicates diagnosis and treatment of tuberculosis (TB), we measured diversity prevalence and associated factors among…

Identifying Hotspots of Multidrug-Resistant Tuberculosis Transmission Using Spatial and Molecular Genetic Data.

Author(s): Zelner JL, Murray MB, Becerra MC, Galea J, Lecca L, Calderon R, Yataco R, Contreras C, Zhang Z, Manjourides J, Grenfell BT, Cohen TJournal: J Infect DisPMID: 26175455 January 2016

We aimed to identify and determine the etiology of "hotspots" of concentrated multidrug-resistant tuberculosis (MDR-tuberculosis) risk in Lima, Peru.