The role of interspecies recombinations in the evolution of antibiotic resistant pneumococci

Author(s): D’Aeth JC, van der Linden MPG, McGee L, De Lencastre HC, Turner P, Song J-H, Lo SW, Gladstone RA, Sá-Leão R, Ko KS, Hanage WP, Beall B, Bentley SD, Croucher NJJournal: bioRxiv February 2021
The evolutionary histories of the antibiotic-resistant Streptococcus pneumoniae lineages PMEN3 and PMEN9 were reconstructed using global collections of genomes. In PMEN3, one…

Frequency-dependent selection can forecast evolution in Streptococcus pneumoniae.

Author(s): Azarian T, Martinez PP, Arnold BJ, Qiu X, Grant LR, Corander J, Fraser C, Croucher NJ, Hammitt LL, Reid R, Santosham M, Weatherholtz RC, Bentley SD, O'Brien KL, Lipsitch M, Hanage WPJournal: PLoS BiolPMID: 33091022 October 2020
Predicting how pathogen populations will change over time is challenging. Such has been the case with Streptococcus pneumoniae, an important…