Author(s): D’Aeth JC, van der Linden MPG, McGee L, de Lencastre H, Turner P, Song JH, Lo SW, Gladstone RA, Sá-Leão R, Ko KS, Hanage WP, Breiman RF, Beall B, Bentley SD, Croucher NJ, GPS Consortium.|Journal: Elife|PMID:34259624| July 2021
Multidrug-resistant emerge through the modification of core genome loci through short inter-species homologous recombinations and acquisition of gene cassettes. Both…
Author(s): Campo JJ, Le TQ, Pablo JV, Hung C, Teng AA, Tettelin H, Tate A, Hanage WP, Alderson MR, Liang X, Malley R, Lipsitch M, Croucher NJ|Journal: Elife|PMID:30592459| December 2018
Pneumococcal whole cell vaccines (WCVs) could cost-effectively protect against a greater strain diversity than current capsule-based vaccines. Immunoglobulin G (IgG)…
Prokaryotic evolution is affected by horizontal transfer of genetic material through recombination. Inference of an evolutionary tree of bacteria thus…
Author(s): Lehtinen S, Blanquart F, Croucher NJ, Turner P, Lipsitch M, Fraser C|Journal: Proc Natl Acad Sci U S A|PMID:28096340| January 2017
Understanding how changes in antibiotic consumption affect the prevalence of antibiotic resistance in bacterial pathogens is important for public health.…
Author(s): Croucher NJ, Campo JJ, Le TQ, Liang X, Bentley SD, Hanage WP, Lipsitch M|Journal: Proc Natl Acad Sci U S A|PMID:28053228| January 2017
Characterizing the immune response to pneumococcal proteins is critical in understanding this bacterium's epidemiology and vaccinology. Probing a custom-designed proteome…
