Publications – Center for Communicable Disease Dynamics

Immunization, Antibiotic Use, and Pneumococcal Colonization Over a 15-Year Period.

Author(s): Lee GM, Kleinman K, Pelton S, Lipsitch M, Huang SS, Lakoma M, Dutta-Linn M, Rett M, Hanage WP, Finkelstein JAJournal: PediatricsPMID: 28978716 November 2017

Rates of invasive pneumococcal disease have declined since widespread introduction of pneumococcal conjugate vaccines (PCVs) in the United States. We…

Stability of the pneumococcal population structure in Massachusetts as PCV13 was introduced.

Author(s): Chang Q, Stevenson AE, Croucher NJ, Lee GM, Pelton SI, Lipsitch M, Finkelstein JA, Hanage WPJournal: BMC Infect DisPMID: 25887323 February 2015

The success of 7-valent pneumococcal conjugate vaccination (PCV-7) introduced to the US childhood immunization schedule in 2000 was partially offset…

Population genomics of post-vaccine changes in pneumococcal epidemiology.

Author(s): Croucher NJ, Finkelstein JA, Pelton SI, Mitchell PK, Lee GM, Parkhill J, Bentley SD, Hanage WP, Lipsitch MJournal: Nat GenetPMID: 23644493 June 2013

Whole-genome sequencing of 616 asymptomatically carried Streptococcus pneumoniae isolates was used to study the impact of the 7-valent pneumococcal conjugate…

Pneumococcal carriage and antibiotic resistance in young children before 13-valent conjugate vaccine.

Author(s): Wroe PC, Lee GM, Finkelstein JA, Pelton SI, Hanage WP, Lipsitch M, Stevenson AE, Rifas-Shiman SL, Kleinman K, Dutta-Linn MM, Hinrichsen VL, Lakoma M, Huang SSJournal: Pediatr Infect Dis JPMID: 22173142 March 2012

We sought to measure trends in Streptococcus pneumoniae carriage and antibiotic resistance in young children in Massachusetts communities after widespread…

Clonal replacement among 19A Streptococcus pneumoniae in Massachusetts, prior to 13 valent conjugate vaccination.

Author(s): Hanage WP, Bishop CJ, Lee GM, Lipsitch M, Stevenson A, Rifas-Shiman SL, Pelton SI, Huang SS, Finkelstein JAJournal: VaccinePMID: 21964059 November 2011

As part of an ongoing study of the response of the Streptococcus pneumoniae population to conjugate vaccination, we applied multi-locus…

Serotype specific invasive capacity and persistent reduction in invasive pneumococcal disease.

Author(s): Yildirim I, Hanage WP, Lipsitch M, Shea KM, Stevenson A, Finkelstein J, Huang SS, Lee GM, Kleinman K, Pelton SIJournal: VaccinePMID: 21029807 December 2010

Defining the propensity of Streptococcus pneumoniae (SP) serotypes to invade sterile body sites following nasopharyngeal (NP) acquisition has the potential…