Publications – Center for Communicable Disease Dynamics

Bayesian modeling of the impact of antibiotic resistance on the efficiency of MRSA decolonization.

Author(s): Ojala F, Sater MRA, Miller LG, McKinnell JA, Hayden MK, Huang SS, Grad YH, Marttinen PJournal: PLoS Comput BiolPMID: 37883601 October 2023

Methicillin-resistant Staphylococcus aureus (MRSA) is a major cause of morbidity and mortality. Colonization by MRSA increases the risk of infection…

Epidemiology and genomics of a slow outbreak of methicillin-resistant Staphyloccus aureus (MRSA) in a neonatal intensive care unit: Successful chronic decolonization of MRSA-positive healthcare personnel

Author(s): Quan KA, Sater MRA, Uy C, Clifton-Koeppel R, Dickey LL, Wilson W, Patton P, Chang W, Samuelson P, Lagoudas GK, Allen T, Merchant L, Gannotta R, Bittencourt CE, Soto JC, Evans KD, Blainey PC, Murray J, Shelton D, Lee HS, Zahn M, Wolfe J, Madey K, Yim J, Gohil SK, Grad YH, Huang SSJournal: Infect Control Hosp EpidemiolPMID: 35706396 June 2022

Objective: To describe the genomic analysis and epidemiologic response related to a slow and prolonged methicillin-resistant Staphylococcus aureus (MRSA) outbreak.…

Epidemiology and genomics of a slow outbreak of methicillin-resistant Staphyloccus aureus (MRSA) in a neonatal intensive care unit: Successful chronic decolonization of MRSA-positive healthcare personnel.

To describe the genomic analysis and epidemiologic response related to a slow and prolonged methicillin-resistant (MRSA) outbreak.

Modelling methicillin-resistant Staphylococcus aureus decolonization: interactions between body sites and the impact of site-specific clearance.

Author(s): Poyraz O, Sater MRA, Miller LG, McKinnell JA, Huang SS, Grad YH, Marttinen PJournal: J R Soc InterfacePMID: 35702866 June 2022

Methicillin-resistant (MRSA) can colonize multiple body sites, and carriage is a risk factor for infection. Successful decolonization protocols reduce disease…

Post-discharge decolonization of patients harboring methicillin-resistant Staphylococcus aureus (MRSA) USA300 strains: secondary analysis of the CLEAR Trial.

Author(s): Gussin GM, Heim L, Tjoa T, McKinnell JA, Miller LG, Gillen DL, Sater MRA, Grad YH, Singh RD, Huang SSJournal: Infect Control Hosp EpidemiolPMID: 34913422 December 2021

The CLEAR Trial recently found that decolonization reduced infections and hospitalizations in MRSA carriers in the year following hospital discharge.…

Modeling MRSA decolonization: Interactions between body sites and the impact of site-specific clearance

Author(s): Poyraz O, Sater MRA, Miller LG, McKinnell JA, Huang SS, Grad Y, Marttinen PJournal: medRxiv March 2021

Methicillin-resistant Staphylococcus aureus (MRSA) colonizes multiple body sites, and carriage is an important risk factor for MRSA infection. Successful decolonization…

The impact of site-specific clearance on methicillin-resistant staphylococcus aureus decolonization

Author(s): Poyraz O, Sater MRA, Miller LG, McKinnell JA, Huang SS, Grad YJournal: medRxiv December 2020

Methicillin-resistant Staphylococcus aureus (MRSA) colonizes multiple body sites, and carriage is an important risk factor for MRSA infection. Successful decolonization…

Immunization, Antibiotic Use, and Pneumococcal Colonization Over a 15-Year Period.

Author(s): Lee GM, Kleinman K, Pelton S, Lipsitch M, Huang SS, Lakoma M, Dutta-Linn M, Rett M, Hanage WP, Finkelstein JAJournal: PediatricsPMID: 28978716 November 2017

Rates of invasive pneumococcal disease have declined since widespread introduction of pneumococcal conjugate vaccines (PCVs) in the United States. We…

Multi-institute analysis of carbapenem resistance reveals remarkable diversity, unexplained mechanisms, and limited clonal outbreaks.

Author(s): Cerqueira GC, Earl AM, Ernst CM, Grad YH, Dekker JP, Feldgarden M, Chapman SB, Reis-Cunha JL, Shea TP, Young S, Zeng Q, Delaney ML, Kim D, Peterson EM, O'Brien TF, Ferraro MJ, Hooper DC, Huang SS, Kirby JE, Onderdonk AB, Birren BW, Hung DT, Cosimi LA, Wortman JR, Murphy CI, Hanage WPJournal: Proc Natl Acad Sci U S APMID: 28096418 January 2017

Carbapenem-resistant Enterobacteriaceae (CRE) are among the most severe threats to the antibiotic era. Multiple different species can exhibit resistance due…

Identifying the effect of patient sharing on between-hospital genetic differentiation of methicillin-resistant Staphylococcus aureus.

Author(s): Chang HH, Dordel J, Donker T, Worby CJ, Feil EJ, Hanage WP, Bentley SD, Huang SS, Lipsitch MJournal: Genome MedPMID: 26873713 February 2016

Methicillin-resistant Staphylococcus aureus (MRSA) is one of the most common healthcare-associated pathogens. To examine the role of inter-hospital patient sharing…