Publications – Center for Communicable Disease Dynamics

Addendum: Estimating clinical severity of COVID-19 from the transmission dynamics in Wuhan, China.

Author(s): Wu JT, Leung K, Kishore N, Niehus R, De Salazar PM, Cowling BJ, Lipsitch M, Leung GMJournal: Nat MedPMID: 32661399 May 2020

On 17 April 2020, the Wuhan Municipal Health Commission revised the official COVID-19 death counts in Wuhan up by 1,290…

Estimating clinical severity of COVID-19 from the transmission dynamics in Wuhan, China.

Author(s): Wu JT, Leung K, Bushman M, Kishore N, Niehus R, De Salazar PM, Cowling BJ, Lipsitch M, Leung GMJournal: Nat MedPMID: 32284616 March 2020

As of 29 February 2020 there were 79,394 confirmed cases and 2,838 deaths from COVID-19 in mainland China. Of these,…

Cost-effectiveness of bivalent versus monovalent vaccines against hand, foot and mouth disease.

Author(s): Liu D, Leung K, Jit M, Yu H, Yang J, Liao Q, Liu F, Zheng Y, Wu JTJournal: Clin Microbiol InfectPMID: 31279839 August 2019

Enterovirus 71 (EV71) and coxsackievirus A16 (CA16) were responsible for 43.3% (235,123/543,243) and 24.8% (134,607/543,243) of all laboratory-confirmed hand, foot…

Assessing the impact of respiratory infections and weather conditions on donor attendance and blood inventory in Hong Kong.

Author(s): Leung K, Lee CK, Lau EHY, Lau CW, Wu JTJournal: Vox SangPMID: 30623977 January 2019

Maintaining a stable, safe and sufficient blood supply is crucial to the healthcare system. Every year, seasonal influenza epidemics lead…

Economic costs and health-related quality of life for hand, foot and mouth disease (HFMD) patients in China.

Author(s): Zheng Y, Jit M, Wu JT, Yang J, Leung K, Liao Q, Yu HJournal: PLoS OnePMID: 28934232 September 2017

Hand, foot and mouth disease (HFMD) is a common illness in China that mainly affects infants and children. The objective…

Social contact patterns relevant to the spread of respiratory infectious diseases in Hong Kong.

Author(s): Leung K, Jit M, Lau EHY, Wu JTJournal: Sci RepPMID: 28801623 August 2017

The spread of many respiratory infections is determined by contact patterns between infectious and susceptible individuals in the population. There…

Monitoring the fitness of antiviral-resistant influenza strains during an epidemic: a mathematical modelling study.

Author(s): Leung K, Lipsitch M, Yuen KY, Wu JTJournal: Lancet Infect DisPMID: 27914853 March 2017

Antivirals (eg, oseltamivir) are important for mitigating influenza epidemics. In 2007, an oseltamivir-resistant influenza seasonal A H1N1 strain emerged and…

Preexisting Antibody-Dependent Cellular Cytotoxicity-Activating Antibody Responses Are Stable Longitudinally and Cross-reactive Responses Are Not Boosted by Recent Influenza Exposure.

Author(s): Valkenburg SA, Zhang Y, Chan KY, Leung K, Wu JT, Poon LLJournal: J Infect DisPMID: 27493238 October 2016

Cross-reactive influenza virus-specific antibody-dependent cellular cytotoxicity (ADCC)-activating antibodies are readily detected in healthy adults. However, little is known about the…

Correction: Routine Pediatric Enterovirus 71 Vaccination in China: a Cost-Effectiveness Analysis.

Author(s): Wu JT, Jit M, Zheng Y, Leung K, Xing W, Yang J, Liao Q, Cowling BJ, Yang B, Lau EH, Takahashi S, Farrar JJ, Grenfell BT, Leung GM, Yu HJournal: PLoS MedPMID: 27050103 April 2016

[This corrects the article DOI: 10.1371/journal.pmed.1001975.].

Routine Pediatric Enterovirus 71 Vaccination in China: a Cost-Effectiveness Analysis.

Author(s): Wu JT, Jit M, Zheng Y, Leung K, Xing W, Yang J, Liao Q, Cowling BJ, Yang B, Lau EH, Takahashi S, Farrar JJ, Grenfell BT, Leung GM, Yu HJournal: PLoS MedPMID: 26978565 March 2016

China accounted for 87% (9.8 million/11.3 million) of all hand, foot, and mouth disease (HFMD) cases reported to WHO during…