Perfect as the enemy of the good: Using low-sensitivity tests to mitigate SARS-CoV-2 outbreaks Author(s): Hanage W, Kennedy-Shaffer L, Baym M|Journal: DASH| July 2020 Preventing future infection waves of COVID-19 will depend on effective and efficient contact tracing. SARS-CoV-2 transmission appears to be characterized…
Host population structure and treatment frequency maintain balancing selection on drug resistance. Author(s): Cobey S, Baskerville EB, Colijn C, Hanage W, Fraser C, Lipsitch M|Journal: J R Soc Interface|PMID: 28835542| August 2017 It is a truism that antimicrobial drugs select for resistance, but explaining pathogen- and population-specific variation in patterns of resistance…
What is the mechanism for persistent coexistence of drug-susceptible and drug-resistant strains of Streptococcus pneumoniae? Author(s): Colijn C, Cohen T, Fraser C, Hanage W, Goldstein E, Givon-Lavi N, Dagan R, Lipsitch M|Journal: J R Soc Interface|PMID: 19940002| June 2010 The rise of antimicrobial resistance in many pathogens presents a major challenge to the treatment and control of infectious diseases.…