Publications – Center for Communicable Disease Dynamics

Spatiotemporal Trends in Group A Streptococcal Pharyngitis in the United States.

Author(s): Kline MC, Kissler SM, Whittles LK, Barnett ML, Grad YHJournal: medRxivPMID: 38014331 November 2023

Group A (GAS) causes an estimated 5.2 million outpatient visits for pharyngitis annually in the United States (U.S.) with incidence…

The “Bubble”: What Can Be Learned from the National Basketball Association (NBA)’s 2019-20 Season Restart in Orlando during the COVID-19 Pandemic.

Author(s): Mack CD, Merson MH, Sims L, Maragakis LL, Davis R, Tai CG, Meisel P, Grad YH, Ho DD, Anderson DJ, LeMay C, DiFiori JJournal: J Appl Lab MedPMID: 37902472 October 2023

The National Basketball Association (NBA) suspended operations in response to the COVID-19 pandemic in March 2020. To safely complete the…

Bayesian modeling of the impact of antibiotic resistance on the efficiency of MRSA decolonization.

Author(s): Ojala F, Sater MRA, Miller LG, McKinnell JA, Hayden MK, Huang SS, Grad YH, Marttinen PJournal: PLoS Comput BiolPMID: 37883601 October 2023

Methicillin-resistant Staphylococcus aureus (MRSA) is a major cause of morbidity and mortality. Colonization by MRSA increases the risk of infection…

Estimating changes in antibiotic consumption in the USA with the introduction of doxycycline post-exposure prophylaxis.

Author(s): Roster KIO, Grad YHJournal: Lancet MicrobePMID: 37883986 October 2023

Viral kinetics of sequential SARS-CoV-2 infections.

Author(s): Kissler SM, Hay JA, Fauver JR, Mack C, Tai CG, Anderson DJ, Ho DD, Grubaugh ND, Grad YHJournal: Nat CommunPMID: 37798265 October 2023

The impact of a prior SARS-CoV-2 infection on the progression of subsequent infections has been unclear. Using a convenience sample…

Estimating changes in antibiotic consumption with the introduction of doxycycline post-exposure prophylaxis in the United States.

Author(s): Roster KIO, Grad YHJournal: medRxivPMID: 37790567 September 2023

Doxycycline as post-exposure prophylaxis (doxy-PEP) reduces the risk of gonorrhea, chlamydia, and syphilis in studies of men who have sex…

Optimal environmental testing frequency for outbreak surveillance

Author(s): Olejarz JW, Oliveira Roster KI, Kissler SM, Lipsitch M, Grad YHJournal: medRxiv September 2023

Public health surveillance for pathogens presents an optimization problem: we require enough sampling to identify intervention-triggering shifts in pathogen epidemiology,…

The Impact of Rapid Drug Susceptibility Tests on Gonorrhea Burden and Lifespan of Antibiotic Treatments: A Modeling Study Among Men Who Have Sex With Men in the United States

Author(s): Yaesoubi R, Xi Q, Hsu K, Gift TL, St Cyr SB, Rönn MM, Salomon JA, Grad YHJournal: American Journal of Epidemiology August 2023

Rapid point-of-care tests that diagnose gonococcal infections and identify susceptibility to antibiotics enable individualized treatment. This could improve patient outcomes…

Resistance-minimising strategies for introducing a novel antibiotic for gonorrhoea treatment: a mathematical modelling study

Author(s): Reichert E, Yaesoubi R, Rönn MM, Gift TL, Salomon JA, Grad YHJournal: Lancet MicrobePMID: 37619582 August 2023

Gonorrhoea is a highly prevalent sexually transmitted infection and an urgent public health concern because of increasing antibiotic resistance in…

The inter-continental population dynamics of Neisseria gonorrhoeae

Author(s): Osnes MN, Brynildsrud OB, Alfsnes K, McKeand SA, Ross J, Town K, de Korne-Elenbaas J, van Dam A, Bruisten S, de Blasio BF, Caugant DA, Grad YH, Williamson DA, Balloux F, Didelot X, Eldholm V, Van Dorp LJournal: bioRxiv August 2023

Neisseria gonorrhoeae is a globally distributed sexually transmitted bacterial pathogen. Recent studies have revealed that its evolution has been shaped…