Publications

Genome wide association studies define minimal set of loci for prediction of penicillin and tetracycline susceptibility in Neisseria gonorrhoeae

Author(s): Mortimer TD, Zhang JJ, Ma KC, Grad YH|Journal: bioRxiv| August 2021

While Neisseria gonorrhoeae poses an urgent public health threat because of increasing antimicrobial resistance, much of the circulating population remains…

Evidence Of Respiratory Infection Transmission Within Physician Offices Could Inform Outpatient Infection Control.

Author(s): Neprash HT, Sheridan B, Jena AB, Grad YH, Barnett ML|Journal: Health Aff (Millwood)|PMID: 34339241| August 2021

Early in the COVID-19 pandemic, outpatient clinics throughout the US shifted toward virtual care to limit viral transmission in the…

Viral dynamics of acute SARS-CoV-2 infection and applications to diagnostic and public health strategies.

Author(s): Kissler SM, Fauver JR, Mack C, Olesen SW, Tai C, Shiue KY, Kalinich CC, Jednak S, Ott IM, Vogels CBF, Wohlgemuth J, Weisberger J, DiFiori J, Anderson DJ, Mancell J, Ho DD, Grubaugh ND, Grad YH|Journal: PLoS Biol|PMID: 34252080| July 2021

SARS-CoV-2 infections are characterized by viral proliferation and clearance phases and can be followed by low-level persistent viral RNA shedding.…

Identification of bile acid and fatty acid species as candidate rapidly bactericidal agents for topical treatment of gonorrhoea.

Author(s): Palace SG, Fryling KE, Li Y, Wentworth AJ, Traverso G, Grad YH|Journal: J Antimicrob Chemother|PMID: 34245280| July 2021

Novel therapeutic strategies are urgently needed for Neisseria gonorrhoeae, given its increasing antimicrobial resistance. Treatment of oropharyngeal N. gonorrhoeae infections…

Test negative designs with uncertainty, sensitivity, and specificity

Author(s): Johnson EK, Kahn R, Grad YH, Lipsitch M, Larremore DB|Journal: medRxiv| June 2021

Test-negative designs (TNDs) can be used to estimate vaccine effectiveness by comparing the relative rates of the target disease and…

Viral dynamics of acute SARS-CoV-2 infection

Author(s): Kissler SM, Fauver JR, Mack C, Olesen SW, Tai C, Shiue KY, Kalinich C, Jednak S, Ott I, Vogels C, Wohlgemuth J, Weisberger J, DiFiori J, Anderson DJ, Mancell J, Ho D, Grubaugh ND, Grad YH|Journal: medRxiv| June 2021

SARS-CoV-2 infections are characterized by viral proliferation and clearance phases and can be followed by low-level viral RNA shedding. The…

Modeling the impact of racial and ethnic disparities on COVID-19 epidemic dynamics.

Author(s): Ma KC, Menkir TF, Kissler SM, Grad YH, Lipsitch M|Journal: Elife|PMID: 34003112| May 2021

The impact of variable infection risk by race and ethnicity on the dynamics of SARS CoV-2 spread is largely unknown.

Childhood respiratory outpatient visits correlate with socioeconomic status and drive geographic patterns in antibiotic prescribing.

Author(s): Kissler SM, Klevens RM, Barnett ML, Grad YH|Journal: J Infect Dis|PMID: 33903899| April 2021

Reducing geographic disparities in antibiotic prescribing is a central public health priority to combat antibiotic resistance, but the drivers of…

SARS-CoV-2 Transmission Risk Among National Basketball Association Players, Staff, and Vendors Exposed to Individuals With Positive Test Results After COVID-19 Recovery During the 2020 Regular and Postseason.

Author(s): Mack CD, DiFiori J, Tai CG, Shiue KY, Grad YH, Anderson DJ, Ho DD, Sims L, LeMay C, Mancell J, Maragakis LL|Journal: JAMA Intern Med|PMID: 33885715| April 2021

Clinical data are lacking regarding the risk of viral transmission from individuals who have positive reverse-transcription-polymerase chain reaction (RT-PCR) SARS-CoV-2…

A community-driven resource for genomic epidemiology and antimicrobial resistance prediction of Neisseria gonorrhoeae at Pathogenwatch.

Author(s): Sánchez-Busó L, Yeats CA, Taylor B, Goater RJ, Underwood A, Abudahab K, Argimón S, Ma KC, Mortimer TD, Golparian D, Cole MJ, Grad YH, Martin I, Raphael BH, Shafer WM, Town K, Wi T, Harris SR, Unemo M, Aanensen DM|Journal: Genome Med|PMID: 33875000| April 2021