Publications – Center for Communicable Disease Dynamics

Drivers of Geographic Patterns in Outpatient Antibiotic Prescribing in the United States.

Author(s): Kissler SM, Oliveira Roster KI, Petherbridge R, Mehrotra A, Barnett ML, Grad YHJournal: Clin Infect DisPMID: 38509670 March 2024

In a retrospective, ecological analysis of US medical claims, visit rates explained more of the geographic variation in outpatient antibiotic…

Optimal environmental testing frequency for outbreak surveillance.

Author(s): Olejarz JW, Roster KIO, Kissler SM, Lipsitch M, Grad YHJournal: EpidemicsPMID: 38394927 March 2024

Public health surveillance for pathogens presents an optimization problem: we require enough sampling to identify intervention-triggering shifts in pathogen epidemiology,…

Low antibody levels associated with significantly increased rate of SARS-CoV-2 infection in a highly vaccinated population from the US National Basketball Association.

Author(s): Tai CG, Haviland MJ, Kissler SM, Lucia RM, Merson M, Maragakis LL, Ho DD, Anderson DJ, DiFiori J, Grubaugh ND, Grad YH, Mack CDJournal: J Med VirolPMID: 38465748 March 2024

SARS-CoV-2 antibody levels may serve as a correlate for immunity and could inform optimal booster timing. The relationship between antibody…

Spatiotemporal Trends in Group A Streptococcal Pharyngitis in the United States.

Author(s): Kline MC, Kissler SM, Whittles LK, Barnett ML, Grad YHJournal: Clin Infect DisPMID: 38373257 February 2024

Group A Streptococcus (GAS) causes an estimated 5.2 million outpatient visits for pharyngitis annually in the United States (U.S.) with…

Spatiotemporal Trends in Group A Streptococcal Pharyngitis in the United States.

Author(s): Kline MC, Kissler SM, Whittles LK, Barnett ML, Grad YHJournal: medRxivPMID: 38014331 November 2023

Group A (GAS) causes an estimated 5.2 million outpatient visits for pharyngitis annually in the United States (U.S.) with incidence…

Viral kinetics of sequential SARS-CoV-2 infections.

Author(s): Kissler SM, Hay JA, Fauver JR, Mack C, Tai CG, Anderson DJ, Ho DD, Grubaugh ND, Grad YHJournal: Nat CommunPMID: 37798265 October 2023

The impact of a prior SARS-CoV-2 infection on the progression of subsequent infections has been unclear. Using a convenience sample…

Optimal environmental testing frequency for outbreak surveillance

Author(s): Olejarz JW, Oliveira Roster KI, Kissler SM, Lipsitch M, Grad YHJournal: medRxiv September 2023

Public health surveillance for pathogens presents an optimization problem: we require enough sampling to identify intervention-triggering shifts in pathogen epidemiology,…

Surveillance strategies for the detection of new SARS-CoV-2 variants across epidemiological contexts

Author(s): Roster KIO, Kissler SM, Omoregie E, Wang JC, Amin H, Lonardo SD, Hughes S, Grad YHJournal: medRxiv May 2023

Rapid identification of new SARS-CoV-2 variants is a critical component of the public health response to the COVID-19 pandemic. However,…

Quantifying the impact of immune history and variant on SARS-CoV-2 viral kinetics and infection rebound: a retrospective cohort study

Author(s): Hay JA, Kissler SM, Fauver JR, Mack C, Tai CG, Samant RM, Connolly S, Anderson DJ, Khullar G, MacKay M, Patel M, Kelly S, Manhertz A, Eiter I, Salgado D, Baker T, Howard B, Dudley JT, Mason CE, Nair M, Huang Y, DiFiori J, Ho DD, Grubaugh N, Grad YHJournal: ElifePMID: 36383192 November 2022

The combined impact of immunity and SARS-CoV-2 variants on viral kinetics during infections has been unclear. We characterized 1,280 infections…

Impact of respiratory infection and chronic comorbidities on early pediatric antibiotic dispensing in the United States.

Author(s): Kissler SM, Wang B, Mehrotra A, Barnett M, Grad YHJournal: Clin Infect DisPMID: 36196577 October 2022

In the United States, children under age 5 receive high volumes of antibiotics, which may contribute to antibiotic resistance. It…