Publications – Center for Communicable Disease Dynamics

Successful treatment of SARS-CoV-2 in an immunocompromised patient with persistent infection for 245 days: A case report.

Author(s): Overbeck V, Taylor BP, Turcinovic J, Qiu X, Schaeffer B, Seitz S, Curry SR, Hanage WP, Connor JH, Kuppalli KJournal: HeliyonPMID: 38223743 December 2023

Immunocompromised patients receiving B-cell-depleting therapies are at increased risk of persistent SARS-CoV-2 infection, with many experiencing fatal outcomes. We report…

Prediction of post-PCV13 pneumococcal evolution using invasive disease data enhanced by inverse-invasiveness weighting.

Author(s): Qiu X, McGee L, Hammitt LL, Grant LR, O'Brien KL, Hanage WP, Lipsitch MJournal: medRxivPMID: 38168234 December 2023

After introduction of pneumococcal conjugate vaccines (PCVs), serotype replacement occurred in the population of Predicting which pneumococcal clones and serotypes…

Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Sequence Characteristics of Coronavirus Disease 2019 (COVID-19) Persistence and Reinfection.

Author(s): Choudhary MC, Crain CR, Qiu X, Hanage W, Li JZJournal: Clin Infect DisPMID: 33906227 January 2022

Both severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) reinfection and persistent infection have been reported, but sequence characteristics in these…

When intuition falters: repeated testing accuracy during an epidemic.

Author(s): Hay JA, Hellewell J, Qiu XJournal: Eur J EpidemiolPMID: 34322830 July 2021

Widespread, repeated testing using rapid antigen tests to proactively detect asymptomatic SARS-CoV-2 infections has been a promising yet controversial topic…

Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Sequence Characteristics of Coronavirus Disease 2019 (COVID-19) Persistence and Reinfection

Author(s): Choudhary MC, Crain CR, Qiu X, Hanage W, Li JZJournal: Clin Infect Dis June 2021

Both severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) reinfection and persistent infection have been reported, but sequence characteristics in these…

Coming to America: Genomic surveillance and how B.1.1.7 arrived in the US.

Author(s): Qiu X, Hanage WP, Taylor BPJournal: CellPMID: 33989546 May 2021

In this issue of Cell, Washington et al. and Alpert et al. demonstrate the value of genomic surveillance when studying the introduction…

Snowball Sampling Study Design for Serosurveys Early in Disease Outbreaks.

Author(s): Kennedy-Shaffer L, Qiu X, Hanage WPJournal: Am J EpidemiolPMID: 33831177 April 2021

Serological surveys can provide evidence of cases that were not previously detected, depict the spectrum of disease severity, and estimate…

Evaluating the contributions of strategies to prevent SARS-CoV-2 transmission in the healthcare setting: a modelling study.

Author(s): Qiu X, Miller JC, MacFadden DR, Hanage WPJournal: BMJ OpenPMID: 33653758 March 2021

Since its onset, the COVID-19 pandemic has caused significant morbidity and mortality worldwide, with particularly severe outcomes in healthcare institutions…

How to detect and reduce potential sources of biases in studies of SARS-CoV-2 and COVID-19.

Author(s): Accorsi EK, Qiu X, Rumpler E, Kennedy-Shaffer L, Kahn R, Joshi K, Goldstein E, Stensrud MJ, Niehus R, Cevik M, Lipsitch MJournal: Eur J EpidemiolPMID: 33634345 February 2021

In response to the coronavirus disease (COVID-19) pandemic, public health scientists have produced a large and rapidly expanding body of…

Persistence and Evolution of SARS-CoV-2 in an Immunocompromised Host.

Author(s): Choi B, Choudhary MC, Regan J, Sparks JA, Padera RF, Qiu X, Solomon IH, Kuo HH, Boucau J, Bowman K, Adhikari UD, Winkler ML, Mueller AA, Hsu TY, Desjardins M, Baden LR, Chan BT, Walker BD, Lichterfeld M, Brigl M, Kwon DS, Kanjilal S, Richardson ET, Jonsson AH, Alter G, Barczak AK, Hanage WP, Yu XG, Gaiha GD, Seaman MS, Cernadas M, Li JZJournal: N Engl J MedPMID: 33176080 December 2020

A 45-year-old man with severe antiphospholipid syndrome complicated by diffuse alveolar hemorrhage, who was receiving anticoagulation therapy, glucocorticoids, cyclophosphamide, and…