Publications

Evidence-based Decision Making: Infectious Disease Modeling Training for Policymakers in East Africa.

Author(s): Ofori SK, Dankwa EA, Ngwakongnwi E, Amberbir A, Bekele A, Murray MB, Grad YH, Buckee CO, Hedt-Gauthier BL|Journal: Ann. Glob. Health|PMID: 38523847| March 2024

Mathematical modeling of infectious diseases is an important decision-making tool for outbreak control. However, in Africa, limited expertise reduces the…

Who Transmits Tuberculosis to Whom: A Cross-Sectional Analysis of a Cohort Study in Lima, Peru.

Author(s): Trevisi L, Brooks MB, Becerra MC, Calderón RI, Contreras CC, Galea JT, Jimenez J, Lecca LW, Yataco RM, Tovar X, Zhang Z, Murray MB, Huang CC|Journal: Am J Respir Crit Care Med|PMID: 38416532| February 2024

The persistent burden of TB disease emphasizes the need to identify individuals with TB for treatment and those at a…

Interventions to prevent post-tuberculosis sequelae: a systematic review and meta-analysis.

Author(s): Alene KA, Hertzog L, Gilmour B, Clements ACA, Murray MB|Journal: EClinicalMedicine|PMID: 38434448| February 2024

Tuberculosis (TB) remains a global public health challenge, causing substantial mortality and morbidity. While TB treatment has made significant progress,…

Utility of Mycobacterium tuberculosis genome sequencing snapshots to assess transmission dynamics over time.

Author(s): Yuen CM, Huang CC, Millones AK, Calderón RI, Manson AL, Jimenez J, Contreras C, Earl AM, Becerra MC, Lecca L, Murray MB|Journal: J Infect Dis|PMID: 37995298| November 2023

We explored the utility of brief Mycobacterium tuberculosis whole-genome sequencing (WGS) "snapshots" at a sentinel site within Lima, Peru for…

Association between overweight/obesity and multidrug-resistant tuberculosis

Author(s): Peinado J, Lecca L, Jimenez J, Calderon R, Yataco R, Becerra MC, Murray MB|Journal: Rev Peru Med Exp Salud Publica| July 2023

Tuberculosis (TB) affects 8.9 to 11.0 million people and is the cause of death of 1.2 to 1.4 million people…

Latent tuberculosis and depressive symptoms in household contacts of persons with active TB: A cohort study

Author(s): Galea JT, Chu AL, Sweetland A, Jimenez J, Yataco R, Calderon R, Zhang Z, Huang CC, Lecca L, Murray MB|Journal: medRxiv| November 2022

Depression is common among persons with TB and associated with poor clinical outcomes. However, little is known about the relationship…

Spatial scale of tuberculosis transmission in Lima, Peru.

Author(s): Huang CC, Trevisi L, Becerra MC, Calderón RI, Contreras CC, Jimenez J, Lecca LW, Yataco RM, Zhang Z, Murray MB|Journal: Proc Natl Acad Sci U S A|PMID: 36322726| November 2022

Spatially targeted interventions may be effective alternatives to individual or population-based prevention strategies against tuberculosis (TB). However, their efficacy may…

Higher native Peruvian genetic ancestry proportion is associated with tuberculosis progression risk.

Author(s): Asgari S, Luo Y, Huang CC, Zhang Z, Calderon R, Jimenez J, Yataco R, Contreras C, Galea JT, Lecca L, Jones D, Moody DB, Murray MB, Raychaudhuri S|Journal: Cell Genom|PMID: 35873671| July 2022

We investigated whether ancestry-specific genetic factors affect tuberculosis (TB) progression risk in a cohort of admixed Peruvians. We genotyped 2,105…

Treatment Outcomes Among Pregnant Patients With Multidrug-Resistant Tuberculosis: A Systematic Review and Meta-analysis.

Author(s): Alene KA, Murray MB, van de Water BJ, Becerra MC, Atalell KA, Nicol MP, Clements ACA|Journal: JAMA Netw Open|PMID: 35687333| June 2022

The management of multidrug-resistant tuberculosis (MDR-TB) during pregnancy is challenging, yet no systematic synthesis of evidence has accurately measured treatment…

Single-cell eQTL models reveal dynamic T cell state dependence of disease loci.

Author(s): Nathan A, Asgari S, Ishigaki K, Valencia C, Amariuta T, Luo Y, Beynor JI, Baglaenko Y, Suliman S, Price AL, Lecca L, Murray MB, Moody DB, Raychaudhuri S|Journal: Nature|PMID: 35545678| May 2022

Non-coding genetic variants may cause disease by modulating gene expression. However, identifying these expression quantitative trait loci (eQTLs) is complicated…