Author(s): Croucher NJ, Finkelstein JA, Pelton SI, Parkhill J, Bentley SD, Lipsitch M, Hanage WP|Journal: Sci Data|PMID:26528397| October 2015
Streptococcus pneumoniae is common nasopharyngeal commensal bacterium and important human pathogen. Vaccines against a subset of pneumococcal antigenic diversity have…
Author(s): Croucher NJ, Kagedan L, Thompson CM, Parkhill J, Bentley SD, Finkelstein JA, Lipsitch M, Hanage WP|Journal: PLoS Genet|PMID:25826208| March 2015
Streptococcus pneumoniae isolates typically express one of over 90 immunologically distinguishable polysaccharide capsules (serotypes), which can be classified into "serogroups"…
Author(s): Croucher NJ, Coupland PG, Stevenson AE, Callendrello A, Bentley SD, Hanage WP|Journal: Nat Commun|PMID:25407023| November 2014
Bacterial populations often consist of multiple co-circulating lineages. Determining how such population structures arise requires understanding what drives bacterial diversification.…
Author(s): Li Y, Weinberger DM, Thompson CM, TrzciĆski K, Lipsitch M|Journal: Infect Immun|PMID:24082068| December 2013
Streptococcus pneumoniae (pneumococcus) frequently colonizes the human nasopharynx and is an important cause of pneumonia, meningitis, sinusitis, and otitis media.…
Whole-genome sequencing of 616 asymptomatically carried Streptococcus pneumoniae isolates was used to study the impact of the 7-valent pneumococcal conjugate…