Publications – Center for Communicable Disease Dynamics

Adaptive guidelines for the treatment of gonorrhea to increase the effective life span of antibiotics among men who have sex with men in the United States: A mathematical modeling study.

Author(s): Yaesoubi R, Cohen T, Hsu K, Gift TL, Chesson H, Salomon JA, Grad YHJournal: PLoS MedPMID: 32243443 April 2020

The rise of gonococcal antimicrobial resistance highlights the need for strategies that extend the clinically useful life span of antibiotics.…

Accurate quantification of uncertainty in epidemic parameter estimates and predictions using stochastic compartmental models.

Author(s): Zimmer C, Leuba SI, Cohen T, Yaesoubi RJournal: Stat Methods Med ResPMID: 30428780 November 2018

Stochastic transmission dynamic models are needed to quantify the uncertainty in estimates and predictions during outbreaks of infectious diseases. We…

Internal migration and transmission dynamics of tuberculosis in Shanghai, China: an epidemiological, spatial, genomic analysis.

Author(s): Yang C, Lu L, Warren JL, Wu J, Jiang Q, Zuo T, Gan M, Liu M, Liu Q, DeRiemer K, Hong J, Shen X, Colijn C, Guo X, Gao Q, Cohen TJournal: Lancet Infect DisPMID: 29681517 July 2018

Massive internal migration from rural to urban areas poses new challenges for tuberculosis control in China. We aimed to combine…

A Likelihood Approach for Real-Time Calibration of Stochastic Compartmental Epidemic Models.

Author(s): Zimmer C, Yaesoubi R, Cohen TJournal: PLoS Comput BiolPMID: 28095403 January 2017

Stochastic transmission dynamic models are especially useful for studying the early emergence of novel pathogens given the importance of chance…

Identifying cost-effective dynamic policies to control epidemics.

Author(s): Yaesoubi R, Cohen TJournal: Stat MedPMID: 27449759 December 2016

We describe a mathematical decision model for identifying dynamic health policies for controlling epidemics. These dynamic policies aim to select…

Identifying Hotspots of Multidrug-Resistant Tuberculosis Transmission Using Spatial and Molecular Genetic Data.

Author(s): Zelner JL, Murray MB, Becerra MC, Galea J, Lecca L, Calderon R, Yataco R, Contreras C, Zhang Z, Manjourides J, Grenfell BT, Cohen TJournal: J Infect DisPMID: 26175455 January 2016

We aimed to identify and determine the etiology of "hotspots" of concentrated multidrug-resistant tuberculosis (MDR-tuberculosis) risk in Lima, Peru.

How competition governs whether moderate or aggressive treatment minimizes antibiotic resistance.

Author(s): Colijn C, Cohen TJournal: ElifePMID: 26393685 September 2015

Understanding how our use of antimicrobial drugs shapes future levels of drug resistance is crucial. Recently, there has been debate…

How could preventive therapy affect the prevalence of drug resistance? Causes and consequences.

Author(s): Kunkel A, Colijn C, Lipsitch M, Cohen TJournal: Philos Trans R Soc Lond B Biol SciPMID: 25918446 June 2015

Various forms of preventive and prophylactic antimicrobial therapies have been proposed to combat HIV (e.g. pre-exposure prophylaxis), tuberculosis (e.g. isoniazid…

Evaluating the potential impact of enhancing HIV treatment and tuberculosis control programmes on the burden of tuberculosis.

Author(s): Chindelevitch L, Menzies NA, Pretorius C, Stover J, Salomon JA, Cohen TJournal: J R Soc InterfacePMID: 25878131 May 2015

HIV has fuelled increasing tuberculosis (TB) incidence in sub-Saharan Africa. Better control of TB in this region may be achieved…