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Limited available evidence supports theoretical predictions of reduced vaccine efficacy at higher exposure dose.

Author(s): Langwig KE, Gomes MGM, Clark MD, Kwitny M, Yamada S, Wargo AR, Lipsitch M|Journal: Sci Rep|PMID: 30824732| May 2019
Understanding the causes of vaccine failure is important for predicting disease dynamics in vaccinated populations and planning disease interventions. Pathogen…

Vaccine Effects on Heterogeneity in Susceptibility and Implications for Population Health Management.

Author(s): Langwig KE, Wargo AR, Jones DR, Viss JR, Rutan BJ, Egan NA, Sá-Guimarães P, Kim MS, Kurath G, Gomes MGM, Lipsitch M|Journal: MBio|PMID: 29162706| November 2017
Heterogeneity in host susceptibility is a key determinant of infectious disease dynamics but is rarely accounted for in assessment of…

Center for Communicable Disease Dynamics on Twitter

  • RT @HarvardSTS: Join us Dec 7, 1pm (US Eastern) for a roundtable discussion on "Trust in Science, Trust in Democracy" with Marc Lipsit…
  • “We absolutely need to know if these vaccines are going to stop transmission, but no data that we’re going to get i… https://t.co/jtZl3Ptwns
  • Tuesday 12/8 @ 12:30 PM ET: @reichlab will be discussing The #COVID19 Forecast Hub, focusing on how to use statisti… https://t.co/sZOzVhWKEX
  • RT @RadInstitute: As new information about transmission, demographics & treatment of #COVID19 emerge, epidemiologists use complex data to g…
  • @DrEricDing @ritholtz FYI according to Harvard's Director @CCDD_HSPH, Eric Feigl-Ding is a charlatan. More info he… https://t.co/Xh0GAM7akn
  • States have until Friday to submit their #COVID19 vaccine distribution plans. “Health care workers are always at t… https://t.co/OqqkOezdB0
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