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Limited available evidence supports theoretical predictions of reduced vaccine efficacy at higher exposure dose.

Author(s): Langwig KE, Gomes MGM, Clark MD, Kwitny M, Yamada S, Wargo AR, Lipsitch M|Journal: Sci Rep|PMID: 30824732| May 2019
Understanding the causes of vaccine failure is important for predicting disease dynamics in vaccinated populations and planning disease interventions. Pathogen…

Vaccine Effects on Heterogeneity in Susceptibility and Implications for Population Health Management.

Author(s): Langwig KE, Wargo AR, Jones DR, Viss JR, Rutan BJ, Egan NA, Sá-Guimarães P, Kim MS, Kurath G, Gomes MGM, Lipsitch M|Journal: MBio|PMID: 29162706| November 2017
Heterogeneity in host susceptibility is a key determinant of infectious disease dynamics but is rarely accounted for in assessment of…

Center for Communicable Disease Dynamics on Twitter

  • "The existing evidence has not ruled out a laboratory origin, nor has it ruled out a natural origin. It's just pr… https://t.co/nDLMF1KZJk
  • RT @JAMANetworkOpen: Modeling study by @CCDD_HSPH supports frequent screening testing to control nursing home outbreaks of #COVID19 and fin…
  • @CCDD_HSPH @BillHanage This is like playing football and dropping the ball at the 1 yard line. I am sickened by the… https://t.co/OqwBy3bPdh
  • @CCDD_HSPH @BillHanage I am seriously dumbfounded by the idiocy of the CDC’s decision with “If you’re fully Vaccina… https://t.co/4KjBRFRQrM
  • "It’s important to not see this change as a signal that this means that the pandemic is over or that there is no ca… https://t.co/Cv3Yc9DCda
  • RT @WBUR: Prominent local scientists are joining a group of international colleagues who are calling for a thorough investigation to determ…
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