Author(s): Lieberman TD, Wilson D, Misra R, Xiong LL, Moodley P, Cohen T, Kishony R|Journal: Nat Med|PMID:27798613| December 2016
Mycobacterium tuberculosis remains a leading cause of death worldwide, especially among individuals infected with HIV. Whereas phylogenetic analysis has revealed…
Author(s): Cohen T, Chindelevitch L, Misra R, Kempner ME, Galea J, Moodley P, Wilson D|Journal: J Infect Dis|PMID:26768249| June 2016
The clinical management of tuberculosis is a major challenge in southern Africa. The prevalence of within-host genetically heterogeneous Mycobacterium tuberculosis…
Author(s): Chindelevitch L, Colijn C, Moodley P, Wilson D, Cohen T|Journal: PLoS Comput Biol|PMID:26829497| February 2016
Genomic tools have revealed genetically diverse pathogens within some hosts. Within-host pathogen diversity, which we refer to as "complex infection",…
Author(s): Abel zur Wiesch P, Abel S, Gkotzis S, Ocampo P, Engelstädter J, Hinkley T, Magnus C, Waldor MK, Udekwu K, Cohen T|Journal: Sci Transl Med|PMID:25972005| May 2015
Finding optimal dosing strategies for treating bacterial infections is extremely difficult, and improving therapy requires costly and time-intensive experiments. To…
Author(s): Jenkins HE, Plesca V, Ciobanu A, Crudu V, Galusca I, Soltan V, Serbulenco A, Zignol M, Dadu A, Dara M, Cohen T|Journal: Eur Respir J|PMID:23100496| November 2013
Multidrug-resistant tuberculosis (MDR-TB) is a major concern in countries of the former Soviet Union. The reported risk of resistance among…
