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Publications

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Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Sequence Characteristics of Coronavirus Disease 2019 (COVID-19) Persistence and Reinfection.

Author(s): Choudhary MC, Crain CR, Qiu X, Hanage W, Li JZ|Journal: Clin Infect Dis|PMID: 33906227| January 2022
Both severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) reinfection and persistent infection have been reported, but sequence characteristics in these…

When intuition falters: repeated testing accuracy during an epidemic.

Author(s): Hay JA, Hellewell J, Qiu X|Journal: Eur J Epidemiol|PMID: 34322830| July 2021
Widespread, repeated testing using rapid antigen tests to proactively detect asymptomatic SARS-CoV-2 infections has been a promising yet controversial topic…

Variation in human mobility and its impact on the risk of future COVID-19 outbreaks in Taiwan.

Author(s): Chang MC, Kahn R, Li YA, Lee CS, Buckee CO, Chang HH|Journal: BMC Public Health|PMID: 33504339| January 2021
As COVID-19 continues to spread around the world, understanding how patterns of human mobility and connectivity affect outbreak dynamics, especially…

The relation between prescribing of different antibiotics and rates of mortality with sepsis in US adults.

Author(s): Goldstein E, Lipsitch M|Journal: BMC Infect Dis|PMID: 32087679| February 2020
Antibiotic use contributes to the rates of sepsis and the associated mortality, particularly through lack of clearance of resistant infections…

Potential impact of outpatient stewardship interventions on antibiotic exposures of common bacterial pathogens.

Author(s): Tedijanto C, Grad YH, Lipsitch M|Journal: Elife|PMID: 32022685| February 2020
The relationship between antibiotic stewardship and population levels of antibiotic resistance remains unclear. In order to better understand shifts in…

Novel methods for the analysis of stepped wedge cluster randomized trials.

Author(s): Kennedy-Shaffer L, de Gruttola V, Lipsitch M|Journal: Stat Med|PMID: 31876979| December 2019
Stepped wedge cluster randomized trials (SW-CRTs) have become increasingly popular and are used for a variety of interventions and outcomes,…

Levels of outpatient prescribing for four major antibiotic classes and rates of septicemia hospitalization in adults in different US states – a statistical analysis.

Author(s): Goldstein E, Olesen SW, Karaca Z, Steiner CA, Viboud C, Lipsitch M|Journal: BMC Public Health|PMID: 31426780| August 2019
Rates of sepsis/septicemia hospitalization in the US have risen significantly during recent years. Antibiotic resistance and use may contribute to…

The distribution of antibiotic use and its association with antibiotic resistance.

Author(s): Olesen SW, Barnett ML, MacFadden DR, Brownstein JS, Hernández-Díaz S, Lipsitch M, Grad YH|Journal: Elife|PMID: 30560781| December 2018
Antibiotic use is a primary driver of antibiotic resistance. However, antibiotic use can be distributed in different ways in a…

Improving Control of Antibiotic-Resistant Gonorrhea by Integrating Research Agendas Across Disciplines: Key Questions Arising From Mathematical Modeling.

Author(s): Grad YH, Goldstein E, Lipsitch M, White PJ|Journal: J Infect Dis|PMID: 26518045| March 2016
The rise in gonococcal antibiotic resistance and the threat of untreatable infection are focusing attention on strategies to limit the…

Altered drug susceptibility during host adaptation of a Plasmodium falciparum strain in a non-human primate model.

Author(s): Obaldía N 3rd, Dow GS, Gerena L, Kyle D, Otero W, Mantel PY, Baro N, Daniels R, Mukherjee A, Childs LM, Buckee C, Duraisingh MT, Volkman SK, Wirth DF, Marti M|Journal: Sci Rep|PMID: 26880111| February 2016
Infections with Plasmodium falciparum, the most pathogenic of the Plasmodium species affecting man, have been reduced in part due to…

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