Publications – Center for Communicable Disease Dynamics

Assessing thresholds of resistance prevalence at which empiric treatment of gonorrhea should change among men who have sex with men in the US: A cost-effectiveness analysis.

Author(s): Yin X, Li Y, Rönn MM, Li S, Yuan Y, Gift TL, Hsu K, Salomon JA, Grad YH, Yaesoubi RJournal: PLoS MedPMID: 38976754 July 2024

Since common diagnostic tests for gonorrhea do not provide information about susceptibility to antibiotics, treatment of gonorrhea remains empiric. Antibiotics…

Aetiology of vaginal discharge, urethral discharge, and genital ulcer in sub-Saharan Africa: A systematic review and meta-regression.

Author(s): Michalow J, Walters MK, Edun O, Wybrant M, Davies B, Kufa T, Mathega T, Chabata ST, Cowan FM, Cori A, Boily MC, Imai-Eaton JWJournal: PLoS MedPMID: 38768094 June 2024

Syndromic management is widely used to treat symptomatic sexually transmitted infections in settings without aetiologic diagnostics. However, underlying aetiologies and…

Adaptive guidelines for the treatment of gonorrhea to increase the effective life span of antibiotics among men who have sex with men in the United States: A mathematical modeling study.

Author(s): Yaesoubi R, Cohen T, Hsu K, Gift TL, Chesson H, Salomon JA, Grad YHJournal: PLoS MedPMID: 32243443 April 2020

The rise of gonococcal antimicrobial resistance highlights the need for strategies that extend the clinically useful life span of antibiotics.…

Choices in vaccine trial design in epidemics of emerging infections.

Author(s): Kahn R, Rid A, Smith PG, Eyal N, Lipsitch MJournal: PLoS MedPMID: 30086139 August 2018

In a Policy Forum, Marc Lipsitch and colleagues discuss trial design issues in infectious disease outbreaks.

Preprints: An underutilized mechanism to accelerate outbreak science.

Author(s): Johansson MA, Reich NG, Meyers LA, Lipsitch MJournal: PLoS MedPMID: 29614073 April 2018

In an Essay, Michael Johansson and colleagues advocate the posting of research studies addressing infectious disease outbreaks as preprints.

Risk factors and short-term projections for serotype-1 poliomyelitis incidence in Pakistan: A spatiotemporal analysis.

Author(s): Molodecky NA, Blake IM, O'Reilly KM, Wadood MZ, Safdar RM, Wesolowski A, Buckee CO, Bandyopadhyay AS, Okayasu H, Grassly NCJournal: PLoS MedPMID: 28604777 June 2017

Pakistan currently provides a substantial challenge to global polio eradication, having contributed to 73% of reported poliomyelitis in 2015 and…

Ethical alternatives to experiments with novel potential pandemic pathogens.

Author(s): Lipsitch M, Galvani APJournal: PLoS MedPMID: 24844931 May 2014

Predicting the epidemic sizes of influenza A/H1N1, A/H3N2, and B: a statistical method.

Author(s): Goldstein E, Cobey S, Takahashi S, Miller JC, Lipsitch MJournal: PLoS MedPMID: 21750666 July 2011

The epidemic sizes of influenza A/H3N2, A/H1N1, and B infections vary from year to year in the United States. We…

Studies needed to address public health challenges of the 2009 H1N1 influenza pandemic: insights from modeling.

Author(s): Van Kerkhove MD, Asikainen T, Becker NG, Bjorge S, Desenclos JC, dos Santos T, Fraser C, Leung GM, Lipsitch M, Longini IM Jr, McBryde ES, Roth CE, Shay DK, Smith DJ, Wallinga J, White PJ, Ferguson NM, Riley S, WHO Informal Network for Mathematical Modelling for Pandemic Influenza H1N1 2009 (Working Group on Data Needs).Journal: PLoS MedPMID: 20532237 June 2010

In light of the 2009 influenza pandemic and potential future pandemics, Maria Van Kerkhove and colleagues anticipate six public health…

The severity of pandemic H1N1 influenza in the United States, from April to July 2009: a Bayesian analysis.

Author(s): Presanis AM, De Angelis D, New York City Swine Flu Investigation Team., Hagy A, Reed C, Riley S, Cooper BS, Finelli L, Biedrzycki P, Lipsitch MJournal: PLoS MedPMID: 19997612 December 2009

Accurate measures of the severity of pandemic (H1N1) 2009 influenza (pH1N1) are needed to assess the likely impact of an…