Publications – Center for Communicable Disease Dynamics

Carriage burden, multiple colonization and antibiotic pressure promote emergence of resistant vaccine escape pneumococci.

Author(s): Mitchell PK, Lipsitch M, Hanage WPJournal: Philos Trans R Soc Lond B Biol SciPMID: 25918447 June 2015

Pneumococcal conjugate vaccines target the limited subset of the more than 90 known serotypes of Streptococcus pneumoniae responsible for the…

How could preventive therapy affect the prevalence of drug resistance? Causes and consequences.

Author(s): Kunkel A, Colijn C, Lipsitch M, Cohen TJournal: Philos Trans R Soc Lond B Biol SciPMID: 25918446 June 2015

Various forms of preventive and prophylactic antimicrobial therapies have been proposed to combat HIV (e.g. pre-exposure prophylaxis), tuberculosis (e.g. isoniazid…

A sticky situation: the unexpected stability of malaria elimination.

Author(s): Smith DL, Cohen JM, Chiyaka C, Johnston G, Gething PW, Gosling R, Buckee CO, Laxminarayan R, Hay SI, Tatem AJJournal: Philos Trans R Soc Lond B Biol SciPMID: 23798693 June 2013

Malaria eradication involves eliminating malaria from every country where transmission occurs. Current theory suggests that the post-elimination challenges of remaining…

Bacterial genomes in epidemiology–present and future.

Author(s): Croucher NJ, Harris SR, Grad YH, Hanage WPJournal: Philos Trans R Soc Lond B Biol SciPMID: 23382424 February 2013

Sequence data are well established in the reconstruction of the phylogenetic and demographic scenarios that have given rise to outbreaks…