Publications – Center for Communicable Disease Dynamics

How could preventive therapy affect the prevalence of drug resistance? Causes and consequences.

Author(s): Kunkel A, Colijn C, Lipsitch M, Cohen TJournal: Philos Trans R Soc Lond B Biol SciPMID: 25918446 June 2015

Various forms of preventive and prophylactic antimicrobial therapies have been proposed to combat HIV (e.g. pre-exposure prophylaxis), tuberculosis (e.g. isoniazid…

Carriage burden, multiple colonization and antibiotic pressure promote emergence of resistant vaccine escape pneumococci.

Author(s): Mitchell PK, Lipsitch M, Hanage WPJournal: Philos Trans R Soc Lond B Biol SciPMID: 25918447 June 2015

Pneumococcal conjugate vaccines target the limited subset of the more than 90 known serotypes of Streptococcus pneumoniae responsible for the…

A sticky situation: the unexpected stability of malaria elimination.

Author(s): Smith DL, Cohen JM, Chiyaka C, Johnston G, Gething PW, Gosling R, Buckee CO, Laxminarayan R, Hay SI, Tatem AJJournal: Philos Trans R Soc Lond B Biol SciPMID: 23798693 June 2013

Malaria eradication involves eliminating malaria from every country where transmission occurs. Current theory suggests that the post-elimination challenges of remaining…

Bacterial genomes in epidemiology–present and future.

Author(s): Croucher NJ, Harris SR, Grad YH, Hanage WPJournal: Philos Trans R Soc Lond B Biol SciPMID: 23382424 February 2013

Sequence data are well established in the reconstruction of the phylogenetic and demographic scenarios that have given rise to outbreaks…