Publications

Estimating the fitness cost and benefit of antimicrobial resistance from pathogen genomic data.

Author(s): Helekal D, Keeling M, Grad YH, Didelot X|Journal: J R Soc Interface|PMID: 37312496| June 2023

Increasing levels of antibiotic resistance in many bacterial pathogen populations are a major threat to public health. Resistance to an…

Modelling methicillin-resistant Staphylococcus aureus decolonization: interactions between body sites and the impact of site-specific clearance.

Author(s): Poyraz O, Sater MRA, Miller LG, McKinnell JA, Huang SS, Grad YH, Marttinen P|Journal: J R Soc Interface|PMID: 35702866| June 2022

Methicillin-resistant (MRSA) can colonize multiple body sites, and carriage is a risk factor for infection. Successful decolonization protocols reduce disease…

A dynamic, ensemble learning approach to forecast dengue fever epidemic years in Brazil using weather and population susceptibility cycles.

Author(s): McGough SF, Clemente L, Kutz JN, Santillana M|Journal: J R Soc Interface|PMID: 34129785| June 2021

Transmission of dengue fever depends on a complex interplay of human, climate and mosquito dynamics, which often change in time…

The evolution of antibiotic resistance in a structured host population.

Author(s): Blanquart F, Lehtinen S, Lipsitch M, Fraser C|Journal: J R Soc Interface|PMID: 29925579| June 2018

The evolution of antibiotic resistance in opportunistic pathogens such as , or is a major public health problem, as infection…

Exploring the role of competition induced by non-vaccine serotypes for herd protection following pneumococcal vaccination.

Author(s): Masala GL, Lipsitch M, Bottomley C, Flasche S|Journal: J R Soc Interface|PMID: 29093131| November 2017

The competitive pressure from non-vaccine serotypes may have helped pneumococcal conjugate vaccines (PCVs) to limit vaccine-type (VT) serotype prevalence. We…

Host population structure and treatment frequency maintain balancing selection on drug resistance.

Author(s): Cobey S, Baskerville EB, Colijn C, Hanage W, Fraser C, Lipsitch M|Journal: J R Soc Interface|PMID: 28835542| August 2017

It is a truism that antimicrobial drugs select for resistance, but explaining pathogen- and population-specific variation in patterns of resistance…

Introduction of rubella-containing-vaccine to Madagascar: implications for roll-out and local elimination.

Author(s): Wesolowski A, Mensah K, Brook CE, Andrianjafimasy M, Winter A, Buckee CO, Razafindratsimandresy R, Tatem AJ, Heraud JM, Metcalf CJ|Journal: J R Soc Interface|PMID: 27122178| April 2016

Few countries in Africa currently include rubella-containing vaccination (RCV) in their immunization schedule. The Global Alliance for Vaccines Initiative (GAVI)…

Dissecting the determinants of malaria chronicity: why within-host models struggle to reproduce infection dynamics.

Author(s): Childs LM, Buckee CO|Journal: J R Soc Interface|PMID: 25673299| March 2015

The duration of infection is fundamental to the epidemiological behaviour of any infectious disease, but remains one of the most…

The impact of biases in mobile phone ownership on estimates of human mobility.

Author(s): Wesolowski A, Eagle N, Noor AM, Snow RW, Buckee CO|Journal: J R Soc Interface|PMID: 23389897| February 2013

Mobile phone data are increasingly being used to quantify the movements of human populations for a wide range of social,…

Vaccine allocation in a declining epidemic.

Author(s): Goldstein E, Wallinga J, Lipsitch M|Journal: J R Soc Interface|PMID: 22772378| November 2012

Sizeable quantities of 2009 pandemic influenza A/H1N1 (H1N1pdm) vaccine in the USA became available at the end of 2009 when…