Publications – Center for Communicable Disease Dynamics

SARS-CoV-2 breakthrough infections in vaccinated individuals: measurement, causes and impact.

Author(s): Lipsitch M, Krammer F, Regev-Yochay G, Lustig Y, Balicer RDJournal: Nat Rev ImmunolPMID: 34876702 December 2021

Breakthrough infections with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in fully vaccinated individuals are receiving intense scrutiny because of…

Concerns about SARS-CoV-2 evolution should not hold back efforts to expand vaccination.

Author(s): Cobey S, Larremore DB, Grad YH, Lipsitch MJournal: Nat Rev ImmunolPMID: 33795856 April 2021

When vaccines are in limited supply, expanding the number of people who receive some vaccine, such as by halving doses…

Cross-reactive memory T cells and herd immunity to SARS-CoV-2.

Author(s): Lipsitch M, Grad YH, Sette A, Crotty SJournal: Nat Rev ImmunolPMID: 33024281 October 2020

Immunity is a multifaceted phenomenon. For T cell-mediated memory responses to SARS-CoV-2, it is relevant to consider their impact both…

Models of immune selection for multi-locus antigenic diversity of pathogens.

Author(s): Georgieva M, Buckee CO, Lipsitch MJournal: Nat Rev ImmunolPMID: 30479379 January 2019

It is well accepted that pathogens can evade recognition and elimination by the host immune system by varying their antigenic…