Publications – Center for Communicable Disease Dynamics

Snowball Sampling Study Design for Serosurveys Early in Disease Outbreaks.

Author(s): Kennedy-Shaffer L, Qiu X, Hanage WPJournal: Am J EpidemiolPMID: 33831177 April 2021

Serological surveys can provide evidence of cases that were not previously detected, depict the spectrum of disease severity, and estimate…

Potential Biases Arising from Epidemic Dynamics in Observational Seroprotection Studies.

Author(s): Kahn R, Kennedy-Shaffer L, Grad YH, Robins JM, Lipsitch MJournal: Am J EpidemiolPMID: 32870977 September 2020

The extent and duration of immunity following SARS-CoV-2 infection are critical outstanding questions about the epidemiology of this novel virus,…

Statistical Properties of Stepped Wedge Cluster-Randomized Trials in Infectious Disease Outbreaks.

Author(s): Kennedy-Shaffer L, Lipsitch MJournal: Am J EpidemiolPMID: 32648891 July 2020

Randomized controlled trials are crucial for the evaluation of interventions such as vaccinations, but the design and analysis of these…

Accounting for unobserved and differential susceptible time at risk in retrospective studies: response to Dean (2019).

Author(s): Lewnard JA, Tedijanto C, Cowling BJ, Lipsitch MJournal: Am J EpidemiolPMID: 30689694 February 2019

Measurement of Vaccine Direct Effects Under the Test-Negative Design.

Author(s): Lewnard JA, Tedijanto C, Cowling BJ, Lipsitch MJournal: Am J EpidemiolPMID: 30099505 December 2018

Test-negative designs are commonplace in assessments of influenza vaccination effectiveness, estimating this value from the exposure odds ratio of vaccination…

Analyzing Vaccine Trials in Epidemics with Mild and Asymptomatic Infection.

Author(s): Kahn R, Hitchings M, Wang R, Bellan S, Lipsitch MJournal: Am J EpidemiolPMID: 30329134 October 2018

Vaccine efficacy against susceptibility to infection (VES), regardless of symptoms, is an important endpoint of vaccine trials for pathogens with…

Competing Effects Of Indirect Protection And Clustering On The Power Of Cluster-Randomized Controlled Vaccine Trials.

Author(s): Hitchings MDT, Lipsitch M, Wang R, Bellan SEJournal: Am J EpidemiolPMID: 29522080 March 2018

Shared Genomic Variants: Identification of Transmission Routes Using Pathogen Deep-Sequence Data.

Author(s): Worby CJ, Lipsitch M, Hanage WPJournal: Am J EpidemiolPMID: 29149252 November 2017

Sequencing pathogen samples during a communicable disease outbreak is becoming an increasingly common procedure in epidemiologic investigations. Identifying who infected…

Can the Heterosexual HIV Epidemic be Eliminated in South Africa Using Combination Prevention? A Modeling Analysis.

Author(s): Abuelezam NN, McCormick AW, Fussell T, Afriyie AN, Wood R, DeGruttola V, Freedberg KA, Lipsitch M, Seage GR 3rdJournal: Am J EpidemiolPMID: 27416841 August 2016

Little is known about how combining efficacious interventions for human immunodeficiency virus (HIV) prevention could lead to HIV elimination. We…

Utilizing syndromic surveillance data for estimating levels of influenza circulation.

Author(s): Patterson-Lomba O, Van Noort S, Cowling BJ, Wallinga J, Gomes MG, Lipsitch M, Goldstein EJournal: Am J EpidemiolPMID: 24748609 June 2014

The availability of weekly Web-based participatory surveillance data on self-reported influenza-like illness (ILI), defined here as self-reported fever and cough/sore…