A sex-specific evolutionary interaction between ADCY9 and CETP

Author(s): Gamache I, Legault MA, Grenier JC, Sanchez R, Rhéaume E, Asgari S, Barhdadi A, Zada YF, Trochet H, Luo Y, Lecca L, Murray M, Raychaudhuri S, Tardif JC, Dubé MP, Hussin JGJournal: bioRxiv May 2021
Pharmacogenomic studies have revealed associations between rs1967309 in the adenylyl cyclase type 9 (ADCY9) gene and clinical responses to the…

Distinguishing gene flow between malaria parasite populations

Author(s): Brown TS, Taylor AR, Arogbokun O, Buckee CO, Chang HHJournal: bioRxiv January 2021
Measuring gene flow between malaria parasite populations in different geographic locations can provide strategic information for malaria control interventions. Multiple…

Increased antibiotic susceptibility in Neisseria gonorrhoeae through adaptation to the cervical environment

Author(s): Kevin C. Ma, Tatum D. Mortimer, Allison L Hicks, Nicole E Wheeler, Leonor Sánchez-Busó, Daniel Golparian, George Taiaroa, Daniel HF Rubin, Yi Wang, Deborah A Williamson, Magnus Unemo, Simon R. Harris, Yonatan H. GradJournal: bioRxiv May 2020
Neisseria gonorrhoeae is an urgent public health threat due to rapidly increasing incidence and antibiotic resistance. In contrast with the…

Multimodal memory T cell profiling identifies a reduction in a polyfunctional Th17 state associated with tuberculosis progression

Author(s): Aparna Nathan, Jessica I. Beynor, Yuriy Baglaenko, Sara Suliman, Kazuyoshi Ishigaki, Samira Asgari, Chuan-Chin Huang, Yang Luo, Zibiao Zhang, Kattya Lopez Tamara, Judith Jimenez, Roger I. Calderón, Leonid Lecca, Ildiko van Rhijn, D. Branch Moody, Megan B. Murray, Soumya RaychaudhuriJournal: bioRxiv April 2020
Mycobacterium tuberculosis (M.tb) results in 10 million active tuberculosis (TB) cases and 1.5 million deaths each year, making it the…