Publications

Characterizing SARS-CoV-2 Viral Clearance Kinetics to Improve the Design of Antiviral Pharmacometric Studies.

Author(s): Watson JA, Kissler SM, Day NPJ, Grad YH, White NJ|Journal: Antimicrob Agents Chemother|PMID: 35736134| June 2022

A consensus methodology for the pharmacometric assessment of candidate SARS-CoV-2 antiviral drugs would be useful for comparing trial results and…

Using Genetic Distance from Archived Samples for the Prediction of Antibiotic Resistance in Escherichia coli.

Author(s): MacFadden DR, Coburn B, Břinda K, Corbeil A, Daneman N, Fisman D, Lee RS, Lipsitch M, McGeer A, Melano RG, Mubareka S, Hanage WP|Journal: Antimicrob Agents Chemother|PMID: 32152083| March 2020

Rising antibiotic resistance increasingly compromises empiric treatment. Knowing the antibiotic susceptibility of a pathogen's close genetic relative(s) may improve empiric…

In Vitro selection of Neisseria gonorrhoeae mutants with elevated MIC values and increased resistance to cephalosporins.

Author(s): Johnson SR, Grad Y, Ganakammal SR, Burroughs M, Frace M, Lipsitch M, Weil R, Trees D|Journal: Antimicrob Agents Chemother|PMID: 25199775| November 2014

Strains of Neisseria gonorrhoeae with mosaic penA genes bearing novel point mutations in penA have been isolated from ceftriaxone treatment…