Author(s): Arnold B, Sohail M, Wadsworth C, Corander J, Hanage WP, Sunyaev S, Grad YH|Journal: Mol Biol Evol|PMID:31589312| October 2019
Identifying genetic variation in bacteria that has been shaped by ecological differences remains an important challenge. For recombining bacteria, the…
Author(s): Tedijanto C, Olesen SW, Grad YH, Lipsitch M|Journal: Proc Natl Acad Sci U S A|PMID:30559213| December 2018
Bystander selection-the selective pressure for resistance exerted by antibiotics on microbes that are not the target pathogen of treatment-is critical…
Author(s): Olesen SW, Torrone EA, Papp JR, Kirkcaldy RD, Lipsitch M, Grad YH|Journal: J Infect Dis|PMID:30239814| September 2018
Rising azithromycin nonsusceptibility among Neisseria gonorrhoeae threatens current treatment recommendations, but the cause of this rise is not well understood.…
Author(s): Arnold BJ, Gutmann MU, Grad YH, Sheppard SK, Corander J, Lipsitch M, Hanage WP|Journal: Genetics|PMID:29330348| March 2018
The impact of epistasis on the evolution of multi-locus traits depends on recombination. While sexually reproducing eukaryotes recombine so frequently…