Publications – Page 2 – Center for Communicable Disease Dynamics

Infectious disease dynamics and restrictions on social gathering size.

Author(s): Boyer CB, Rumpler E, Kissler SM, Lipsitch MJournal: EpidemicsPMID: 36058184 August 2022

Social gatherings can be an important locus of transmission for many pathogens including SARS-CoV-2. During an outbreak, restricting the size…

Characterizing SARS-CoV-2 Viral Clearance Kinetics to Improve the Design of Antiviral Pharmacometric Studies.

Author(s): Watson JA, Kissler SM, Day NPJ, Grad YH, White NJJournal: Antimicrob Agents ChemotherPMID: 35736134 June 2022

A consensus methodology for the pharmacometric assessment of candidate SARS-CoV-2 antiviral drugs would be useful for comparing trial results and…

Anticipating Racial/Ethnic Mortality Displacement From COVID-19.

Author(s): Kissler SM, Grad YHJournal: Am J EpidemiolPMID: 35452084 April 2022

Analysis of multiple bacterial species and antibiotic classes reveals large variation in the association between seasonal antibiotic use and resistance.

Author(s): Sun DS, Kissler SM, Kanjilal S, Olesen SW, Lipsitch M, Grad YHJournal: PLoS BiolPMID: 35263322 March 2022

Understanding how antibiotic use drives resistance is crucial for guiding effective strategies to limit the spread of resistance, but the…

Viral dynamics and duration of PCR positivity of the SARS-CoV-2 Omicron variant

Author(s): Hay JA, Kissler SM, Fauver JR, Mack C, Tai CG, Samant RM, Connelly S, Anderson DJ, Khullar G, MacKay M, Patel M, Kelly S, Manhertz A, Eiter I, Salgado D, Baker T, Dudley JT, Mason CE, Ho DD, Grubaugh ND, Grad YHJournal: DASH January 2022

The Omicron SARS-CoV-2 variant is responsible for a major wave of COVID-19, with record case counts reflecting high transmissibility and…

Viral Dynamics of SARS-CoV-2 Variants in Vaccinated and Unvaccinated Persons.

Author(s): Kissler SM, Fauver JR, Mack C, Tai CG, Breban MI, Watkins AE, Samant RM, Anderson DJ, Metti J, Khullar G, Baits R, MacKay M, Salgado D, Baker T, Dudley JT, Mason CE, Ho DD, Grubaugh ND, Grad YHJournal: N Engl J MedPMID: 34941024 December 2021

Viral dynamics of acute SARS-CoV-2 infection and applications to diagnostic and public health strategies.

Author(s): Kissler SM, Fauver JR, Mack C, Olesen SW, Tai C, Shiue KY, Kalinich CC, Jednak S, Ott IM, Vogels CBF, Wohlgemuth J, Weisberger J, DiFiori J, Anderson DJ, Mancell J, Ho DD, Grubaugh ND, Grad YHJournal: PLoS BiolPMID: 34252080 July 2021

SARS-CoV-2 infections are characterized by viral proliferation and clearance phases and can be followed by low-level persistent viral RNA shedding.…

Densely sampled viral trajectories suggest longer duration of acute infection with B.1.1.7 variant relative to non-B.1.1.7 SARS-CoV-2

Author(s): Kissler SM, Fauver JR, Mack C, Tai C, Breban M, Watkins AE, Samant R, Anderson D, Ho D, Grubaugh ND, Grad YJournal: medRxiv July 2021

To test whether acute infection with B.1.1.7 is associated with higher or more sustained nasopharyngeal viral concentrations, we assessed longitudinal…

Viral dynamics of acute SARS-CoV-2 infection

Author(s): Kissler SM, Fauver JR, Mack C, Olesen SW, Tai C, Shiue KY, Kalinich C, Jednak S, Ott I, Vogels C, Wohlgemuth J, Weisberger J, DiFiori J, Anderson DJ, Mancell J, Ho D, Grubaugh ND, Grad YHJournal: medRxiv June 2021

SARS-CoV-2 infections are characterized by viral proliferation and clearance phases and can be followed by low-level viral RNA shedding. The…

Modeling the impact of racial and ethnic disparities on COVID-19 epidemic dynamics.

Author(s): Ma KC, Menkir TF, Kissler SM, Grad YH, Lipsitch MJournal: ElifePMID: 34003112 May 2021

The impact of variable infection risk by race and ethnicity on the dynamics of SARS CoV-2 spread is largely unknown.