Publications

Estimating changes in antibiotic consumption in the USA with the introduction of doxycycline post-exposure prophylaxis.

Author(s): Roster KIO, Grad YH|Journal: Lancet Microbe|PMID: 37883986| October 2023

Viral kinetics of sequential SARS-CoV-2 infections.

Author(s): Kissler SM, Hay JA, Fauver JR, Mack C, Tai CG, Anderson DJ, Ho DD, Grubaugh ND, Grad YH|Journal: Nat Commun|PMID: 37798265| October 2023

The impact of a prior SARS-CoV-2 infection on the progression of subsequent infections has been unclear. Using a convenience sample…

Resistance-minimising strategies for introducing a novel antibiotic for gonorrhoea treatment: a mathematical modelling study.

Author(s): Reichert E, Yaesoubi R, Rönn MM, Gift TL, Salomon JA, Grad YH|Journal: Lancet Microbe|PMID: 37619582| October 2023

Gonorrhoea is a highly prevalent sexually transmitted infection and an urgent public health concern because of increasing antibiotic resistance in…

Estimating changes in antibiotic consumption with the introduction of doxycycline post-exposure prophylaxis in the United States.

Author(s): Roster KIO, Grad YH|Journal: medRxiv|PMID: 37790567| September 2023

Doxycycline as post-exposure prophylaxis (doxy-PEP) reduces the risk of gonorrhea, chlamydia, and syphilis in studies of men who have sex…

Optimal environmental testing frequency for outbreak surveillance

Author(s): Olejarz JW, Oliveira Roster KI, Kissler SM, Lipsitch M, Grad YH|Journal: medRxiv| September 2023

Public health surveillance for pathogens presents an optimization problem: we require enough sampling to identify intervention-triggering shifts in pathogen epidemiology,…

Resistance-minimising strategies for introducing a novel antibiotic for gonorrhoea treatment: a mathematical modelling study

Author(s): Reichert E, Yaesoubi R, Rönn MM, Gift TL, Salomon JA, Grad YH|Journal: Lancet Microbe|PMID: 37619582| August 2023

Gonorrhoea is a highly prevalent sexually transmitted infection and an urgent public health concern because of increasing antibiotic resistance in…

The inter-continental population dynamics of Neisseria gonorrhoeae

Author(s): Osnes MN, Brynildsrud OB, Alfsnes K, McKeand SA, Ross J, Town K, de Korne-Elenbaas J, van Dam A, Bruisten S, de Blasio BF, Caugant DA, Grad YH, Williamson DA, Balloux F, Didelot X, Eldholm V, Van Dorp L|Journal: bioRxiv| August 2023

Neisseria gonorrhoeae is a globally distributed sexually transmitted bacterial pathogen. Recent studies have revealed that its evolution has been shaped…

Estimating the fitness cost and benefit of antimicrobial resistance from pathogen genomic data.

Author(s): Helekal D, Keeling M, Grad YH, Didelot X|Journal: J R Soc Interface|PMID: 37312496| June 2023

Increasing levels of antibiotic resistance in many bacterial pathogen populations are a major threat to public health. Resistance to an…

Assessment of sewer connectivity in the United States and its implications for equity in wastewater-based epidemiology

Author(s): Yu QQ, Oleson SW, Duvallet C, Grad YH|Journal: medRxiv| May 2023

Wastewater-based epidemiology is a promising public health tool that can yield a more representative view of the population than case…

O-Antigen Diversification Masks Identification of Highly Pathogenic Shiga Toxin-Producing Escherichia coli O104:H4-Like Strains.

Author(s): Lang C, Fruth A, Campbell IW, Jenkins C, Smith P, Strockbine N, Weill FX, Nübel U, Grad YH, Waldor MK, Flieger A|Journal: Microbiol Spectr|PMID: 37212677| May 2023

Shiga toxin-producing Escherichia coli (STEC) can give rise to a range of clinical outcomes from diarrhea to the life-threatening systemic…