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Publications

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Altered drug susceptibility during host adaptation of a Plasmodium falciparum strain in a non-human primate model.

Author(s): Obaldía N 3rd, Dow GS, Gerena L, Kyle D, Otero W, Mantel PY, Baro N, Daniels R, Mukherjee A, Childs LM, Buckee C, Duraisingh MT, Volkman SK, Wirth DF, Marti M|Journal: Sci Rep|PMID: 26880111| February 2016
Infections with Plasmodium falciparum, the most pathogenic of the Plasmodium species affecting man, have been reduced in part due to…

Targeting Human Transmission Biology for Malaria Elimination.

Author(s): Nilsson SK, Childs LM, Buckee C, Marti M|Journal: PLoS Pathog|PMID: 26086192| June 2015
Malaria remains one of the leading causes of death worldwide, despite decades of public health efforts. The recent commitment by…

Dissecting the determinants of malaria chronicity: why within-host models struggle to reproduce infection dynamics.

Author(s): Childs LM, Buckee CO|Journal: J R Soc Interface|PMID: 25673299| March 2015
The duration of infection is fundamental to the epidemiological behaviour of any infectious disease, but remains one of the most…

Modelling challenges in context: lessons from malaria, HIV, and tuberculosis.

Author(s): Childs LM, Abuelezam NN, Dye C, Gupta S, Murray MB, Williams BG, Buckee CO|Journal: Epidemics|PMID: 25843394| March 2015
Malaria, HIV, and tuberculosis (TB) collectively account for several million deaths each year, with all three ranking among the top…

A Plasmodium falciparum histone deacetylase regulates antigenic variation and gametocyte conversion.

Author(s): Coleman BI, Skillman KM, Jiang RHY, Childs LM, Altenhofen LM, Ganter M, Leung Y, Goldowitz I, Kafsack BFC, Marti M, Llinás M, Buckee CO, Duraisingh MT|Journal: Cell Host Microbe|PMID: 25121747| August 2014
The asexual forms of the malaria parasite Plasmodium falciparum are adapted for chronic persistence in human red blood cells, continuously…

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