Origin and proliferation of multiple-drug resistance in bacterial pathogens. Author(s): Chang HH, Cohen T, Grad YH, Hanage WP, O'Brien TF, Lipsitch M|Journal: Microbiol Mol Biol Rev|PMID: 25652543| March 2015 Many studies report the high prevalence of multiply drug-resistant (MDR) strains. Because MDR infections are often significantly harder and more…
Mycobacterium tuberculosis mutation rate estimates from different lineages predict substantial differences in the emergence of drug-resistant tuberculosis. Author(s): Ford CB, Shah RR, Maeda MK, Gagneux S, Murray MB, Cohen T, Johnston JC, Gardy J, Lipsitch M, Fortune SM|Journal: Nat Genet|PMID: 23749189| July 2013 A key question in tuberculosis control is why some strains of M. tuberculosis are preferentially associated with resistance to multiple…
Modeling the dynamic relationship between HIV and the risk of drug-resistant tuberculosis. Author(s): Sergeev R, Colijn C, Murray M, Cohen T|Journal: Sci Transl Med|PMID: 22623743| May 2012 The emergence of highly drug-resistant tuberculosis (TB) and interactions between TB and HIV epidemics pose serious challenges for TB control.…
What is the mechanism for persistent coexistence of drug-susceptible and drug-resistant strains of Streptococcus pneumoniae? Author(s): Colijn C, Cohen T, Fraser C, Hanage W, Goldstein E, Givon-Lavi N, Dagan R, Lipsitch M|Journal: J R Soc Interface|PMID: 19940002| June 2010 The rise of antimicrobial resistance in many pathogens presents a major challenge to the treatment and control of infectious diseases.…
Negative controls: a tool for detecting confounding and bias in observational studies. Author(s): Lipsitch M, Tchetgen Tchetgen E, Cohen T|Journal: Epidemiology|PMID: 20335814| May 2010 Noncausal associations between exposures and outcomes are a threat to validity of causal inference in observational studies. Many techniques have…
Use of cumulative incidence of novel influenza A/H1N1 in foreign travelers to estimate lower bounds on cumulative incidence in Mexico. Author(s): Lipsitch M, Lajous M, O'Hagan JJ, Cohen T, Miller JC, Goldstein E, Danon L, Wallinga J, Riley S, Dowell SF, Reed C, McCarron M|Journal: PLoS One|PMID: 19742302| September 2009 An accurate estimate of the total number of cases and severity of illness of an emerging infectious disease is required…
