Publications

Origin and proliferation of multiple-drug resistance in bacterial pathogens.

Author(s): Chang HH, Cohen T, Grad YH, Hanage WP, O'Brien TF, Lipsitch M|Journal: Microbiol Mol Biol Rev|PMID: 25652543| March 2015

Many studies report the high prevalence of multiply drug-resistant (MDR) strains. Because MDR infections are often significantly harder and more…

Sequence tag-based analysis of microbial population dynamics.

Author(s): Abel S, Abel zur Wiesch P, Chang HH, Davis BM, Lipsitch M, Waldor MK|Journal: Nat Methods|PMID: 25599549| March 2015

We describe sequence tag-based analysis of microbial populations (STAMP) for characterization of pathogen population dynamics during infection. STAMP analyzes the…

The distribution of pairwise genetic distances: a tool for investigating disease transmission.

Author(s): Worby CJ, Chang HH, Hanage WP, Lipsitch M|Journal: Genetics|PMID: 25313129| December 2014

Whole-genome sequencing of pathogens has recently been used to investigate disease outbreaks and is likely to play a growing role…