Publications

Surface charge of Streptococcus pneumoniae predicts serotype distribution.

Author(s): Li Y, Weinberger DM, Thompson CM, Trzciński K, Lipsitch M|Journal: Infect Immun|PMID: 24082068| December 2013

Streptococcus pneumoniae (pneumococcus) frequently colonizes the human nasopharynx and is an important cause of pneumonia, meningitis, sinusitis, and otitis media.…

Distinct effects on diversifying selection by two mechanisms of immunity against Streptococcus pneumoniae.

Author(s): Li Y, Gierahn T, Thompson CM, Trzciński K, Ford CB, Croucher N, Gouveia P, Flechtner JB, Malley R, Lipsitch M|Journal: PLoS Pathog|PMID: 23144610| January 2012

Antigenic variation to evade host immunity has long been assumed to be a driving force of diversifying selection in pathogens.…

The role of complement in innate and adaptive immunity to pneumococcal colonization and sepsis in a murine model.

Author(s): Bogaert D, Thompson CM, Trzciński K, Malley R, Lipsitch M|Journal: Vaccine|PMID: 19892042| January 2010

Streptococcus pneumoniae is an important bacterial cause of sepsis, meningitis, pneumonia and otitis media. Pneumococcal disease is generally preceded by…