Author(s): Cerqueira GC, Earl AM, Ernst CM, Grad YH, Dekker JP, Feldgarden M, Chapman SB, Reis-Cunha JL, Shea TP, Young S, Zeng Q, Delaney ML, Kim D, Peterson EM, O'Brien TF, Ferraro MJ, Hooper DC, Huang SS, Kirby JE, Onderdonk AB, Birren BW, Hung DT, Cosimi LA, Wortman JR, Murphy CI, Hanage WP|Journal: Proc Natl Acad Sci U S A|PMID:28096418| January 2017
Carbapenem-resistant Enterobacteriaceae (CRE) are among the most severe threats to the antibiotic era. Multiple different species can exhibit resistance due…
Author(s): Lehtinen S, Blanquart F, Croucher NJ, Turner P, Lipsitch M, Fraser C|Journal: Proc Natl Acad Sci U S A|PMID:28096340| January 2017
Understanding how changes in antibiotic consumption affect the prevalence of antibiotic resistance in bacterial pathogens is important for public health.…
Author(s): Croucher NJ, Campo JJ, Le TQ, Liang X, Bentley SD, Hanage WP, Lipsitch M|Journal: Proc Natl Acad Sci U S A|PMID:28053228| January 2017
Characterizing the immune response to pneumococcal proteins is critical in understanding this bacterium's epidemiology and vaccinology. Probing a custom-designed proteome…
Author(s): Harms K, Lunnan A, Hülter N, Mourier T, Vinner L, Andam CP, Marttinen P, Fridholm H, Hansen AJ, Hanage WP, Nielsen KM, Willerslev E, Johnsen PJ|Journal: Proc Natl Acad Sci U S A|PMID:27956618| December 2016
In a screen for unexplained mutation events we identified a previously unrecognized mechanism generating clustered DNA polymorphisms such as microindels…
Author(s): Wesolowski A, Metcalf CJ, Eagle N, Kombich J, Grenfell BT, Bjørnstad ON, Lessler J, Tatem AJ, Buckee CO|Journal: Proc Natl Acad Sci U S A|PMID:26283349| September 2015
Changing patterns of human aggregation are thought to drive annual and multiannual outbreaks of infectious diseases, but the paucity of…
Author(s): Yang W, Lipsitch M, Shaman J|Journal: Proc Natl Acad Sci U S A|PMID:25730851| March 2015
The inference of key infectious disease epidemiological parameters is critical for characterizing disease spread and devising prevention and containment measures.…
