Author(s): Reshef YA, Rumker L, Kang JB, Nathan A, Murray MB, Moody DB, Raychaudhuri S|Journal: bioRxiv| April 2021
As single-cell datasets grow in sample size, there is a critical need to characterize cell states that vary across samples…
Author(s): Suliman S, Kjer-Nielsen L, Iwany S, Lopez K, Loh L, Kedzierska K, Ocampo TA, Corbett A, McCluskey J, Rossjohn J, Leon S, Calderon R, Lecca L, Murray MB, Moody B, Rhijn IV|Journal: bioRxiv| March 2021
Mucosal-associated invariant T (MAIT) cells are innate-like T cells that are highly abundant in human blood and tissues. Most MAIT…
Author(s): Brown TS, Taylor AR, Arogbokun O, Buckee CO, Chang HH|Journal: bioRxiv| January 2021
Measuring gene flow between malaria parasite populations in different geographic locations can provide strategic information for malaria control interventions. Multiple…
Author(s): Daniel B Larremore, Bailey K Fosdick, Sam Zhang, Yonatan H. Grad|Journal: bioRxiv| May 2020
The design and interpretation of prevalence studies rely on point estimates of the performance characteristics of the diagnostic test used.…
Author(s): Kevin C. Ma, Tatum D. Mortimer, Allison L Hicks, Nicole E Wheeler, Leonor Sánchez-Busó, Daniel Golparian, George Taiaroa, Daniel HF Rubin, Yi Wang, Deborah A Williamson, Magnus Unemo, Simon R. Harris, Yonatan H. Grad|Journal: bioRxiv| May 2020
Neisseria gonorrhoeae is an urgent public health threat due to rapidly increasing incidence and antibiotic resistance. In contrast with the…
Author(s): Aparna Nathan, Jessica I. Beynor, Yuriy Baglaenko, Sara Suliman, Kazuyoshi Ishigaki, Samira Asgari, Chuan-Chin Huang, Yang Luo, Zibiao Zhang, Kattya Lopez Tamara, Judith Jimenez, Roger I. Calderón, Leonid Lecca, Ildiko van Rhijn, D. Branch Moody, Megan B. Murray, Soumya Raychaudhuri|Journal: bioRxiv| April 2020
Mycobacterium tuberculosis (M.tb) results in 10 million active tuberculosis (TB) cases and 1.5 million deaths each year, making it the…
Author(s): Aimee R Taylor, Diego F. Echeverry, Timothy J. C. Anderson, Daniel E. Neafsey, Caroline O Buckee|Journal: bioRxiv| April 2020
Characterising connectivity between geographically separated biological populations is a common goal in many fields. Recent approaches to understanding connectivity between…
Author(s): Taj Azarian, Pamela P Martinez, Brian J Arnold, Lindsay R Grant, Jukka Corander, Christophe Fraser, Nicholas J. Croucher, Laura L Hammitt, Raymond Reid, Mathuram Santosham, Robert C Weatherholtz, Stephen D Bentley, Katherine L O’Brien, Marc Lipsitch, William P Hanage|Journal: bioRxiv| February 2020
Predicting how pathogen populations will change over time is challenging. Such has been the case with Streptococcus pneumoniae, an important…
Author(s): Nyamekye Obeng-Adjei, Daniel B Larremore, Louise Turner, Aissata Ongoiba, Shanping Li, Safiatou Doumbo, Takele B. Yazew, Kassoum Kayentao, Louis H. Miller, Boubacar Traore, Susan K. Pierce, Caroline O Buckee, Thomas Lavstsen, Peter D. Crompton, Tuan M. Tran|Journal: bioRxiv| February 2020
Malaria pathogenicity is determined, in part, by the adherence of Plasmodium falciparum infected erythrocytes to the microvasculature mediated via specific…
Author(s): Amy K. Bei, Daniel B Larremore, Kazutoyo Miura, Ababacar Diouf, Nicholas K. Baro, Rachel F. Daniels, Allison Griggs, Eli L. Moss, Daniel E. Neafsey, Awa B. Deme, Mouhamad Sy, Stephen Schaffner, Ambroise D. Ahouidi, Daouda Ndiaye, Tandakha Dieye, Souleymane Mboup, Caroline O Buckee, Sarah K. Volkman, Carole A. Long, Dyann F. Wirth|Journal: bioRxiv| January 2020
As transmission intensity has declined in Senegal, so has the genetic complexity of circulating Plasmodium falciparum parasites, resulting in specific…
